Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB7A | P51149 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 12/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.51 |
| ▸ | PTPRC | P08575 | 3/20 | 0.51 |
| ▸ | PTPRB | P23467 | 2/20 | 0.51 |
| ▸ | PTPRE | P23469 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837176 | 0.86 | PTPN1 (0.50) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL5838517 | 0.82 | PTPN1 (0.48) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6206528 | 0.80 | RAB7A (0.55) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6204620 | 0.79 | PTPN1 (0.53) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL7676326 | 0.78 | PTPN1 (0.49) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6226621 | 0.77 | RAB7A (0.44) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6322130 | 0.76 | RAB7A (0.47) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6315022 | 0.76 | RAB7A (0.51) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6323701 | 0.76 | RAB7A (0.46) | RAB7APTPN1PTPN2PTPRCPTPRB | |
| SCHEMBL6207147 | 0.74 | PTPN1 (0.51) | RAB7APTPN1PTPN2PTPRCPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019026-B1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2006-03-28 | — | — | US | disclosed |