Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.63 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125970 | 0.86 | ERN1 (0.61) | ERN1TRPM4PADI4NQO2GLO1 | |
| SCHEMBL10331758 | 0.86 | PADI4 (0.57) | ERN1TRPM4PADI4NQO2GLO1 | |
| SCHEMBL29407829 | 0.86 | ERN1 (0.61) | ERN1TRPM4PADI4NQO2GLO1 | |
| SCHEMBL5843386 | 0.83 | ERN1 (0.58) | ERN1TRPM4PADI4NQO2GLO1 | |
| SCHEMBL342278 | 0.81 | ERN1 (0.57) | ERN1PADI4KDM4ENPC1CYP1A2 | |
| SCHEMBL29388184 | 0.81 | ERN1 (0.57) | ERN1PADI4KDM4ENPC1CYP1A2 | |
| SCHEMBL3635848 | 0.80 | CYP1A2 (0.59) | ERN1TRPM4PADI4KDM4ECYP1A2 | |
| Methyl Alcohol SCHEMBL27670101 | 0.79 | ERN1 (0.57) | ERN1PADI4GLO1KDM4EHTT | |
| SCHEMBL5843636 | 0.79 | ERN1 (0.53) | ERN1TRPM4PADI4NQO2GLO1 | |
| SCHEMBL5840936 | 0.79 | ERN1 (0.53) | ERN1TRPM4PADI4NQO2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100489027-C | Flame-retardant epoxy resin composition and phosphorus-containing compound | CHANGCHUN ARTIFICIAL RESIN FAC (CN) | 2009-05-20 | — | — | CN | disclosed |
| US-6984716-B2 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-01-10 | — | — | US | disclosed |
| CN-1580120-A | Flame-retardant epoxy resin composition and phosphorus-containing compound | CHANGCHUN ARTIFICIAL RESIN FAC (CN) | 2005-02-16 | — | — | CN | disclosed |
| CN-1580108-A | Phosphorus-containing compound | ARTIFICIAL RESIN FACTORY CO LT (CN) | 2005-02-16 | — | — | CN | disclosed |
| US-20040077825-A1 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-22 | — | — | US | disclosed |
| US-20040038977-A1 | Substituted bezopyran derivatives for the treatment of inflammation | G.D. SEARLE & CO. | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038977-A1 | Substituted bezopyran derivatives for the treatment of inflammation | PTGS1, PTGES2, IL1R1 | ERN1 2376/4885TRPM4 3467/4885PADI4 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.