Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ERN1 | O75460 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.44 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356987 | 0.83 | CYP1A2 (0.59) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL29221780 | 0.83 | MEN1 (0.59) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL5841822 | 0.80 | ERN1 (0.63) | CYP1A2KDM4ECYP2C19ERN1MAPT | |
| SCHEMBL770722 | 0.80 | CYP1A2 (0.70) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL29779946 | 0.79 | CYP1A2 (0.68) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL88986 | 0.79 | CYP1A2 (0.68) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL245378 | 0.79 | CYP1A2 (0.62) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL31149178 | 0.79 | CYP1A2 (0.62) | CYP1A2KDM4EMEN1ALDH1A1GLA | |
| SCHEMBL10331758 | 0.79 | PADI4 (0.57) | ERN1CYP3A4MAPTTRPM4PADI4 | |
| SCHEMBL28999818 | 0.78 | CYP1A2 (0.61) | CYP1A2KDM4EMEN1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557907-B | 2,4, 5-Trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-112236426-B | Process for preparing 2,4, 5-trisubstituted 1,2, 4-triazolones | 拜耳股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113348165-B | 1,2, 4-Triazin-3 (2H) -one compounds for the treatment of hyperproliferative diseases | 拜耳股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-111212647-B | Dihydro oxadiazinones | 拜耳股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114921391-B | 4, 5-cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117186072-A | Compound for inhibiting phosphatidylinositol-3-kinase gamma subtype activity and preparation method and application thereof | 安驰达生物医药技术(广州)有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116829540-A | Condensed nitrogen heterocycles as sigma ligand compounds and uses thereof | 密涅瓦神经科学有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116621907-A | Betulinic acid nucleoside derivatives for preventing or treating cancer | 河南省科学院高新技术研究中心 | 2023-08-22 | — | — | CN | disclosed |
| EP-2160650-A1 | RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH SOLVENT RESISTANT POLY(VINYL ACETAL)S | Eastman Kodak Company (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2009005582-A1 | RADIATION-SENSITIVE COMPOSITIONS AND ELEMENTS WITH SOLVENT RESISTANT POLY(VINYL ACETAL)S | EASTMAN KODAK COMPANY (US) | 2009-01-08 | — | — | WO | disclosed |