Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5844488 | 0.88 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5843692 | 0.85 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5843928 | 0.82 | ALDH1A1 (0.67) | ALDH1A1 | |
| SCHEMBL5842722 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5844459 | 0.82 | TP53 (0.63) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5842727 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5841861 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5843662 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5841403 | 0.80 | MAPT (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5841855 | 0.79 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067549-B2 | Pyrrolidone carboxamides | ACTELION PHARMACEUTICALS AG (CH) | 2006-06-27 | — | — | US | disclosed |