SCHEMBL584267

SCHEMBL584267

COCCCN1CCNCC1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CXCR4 P61073 2/20 0.50
HRH2 P25021 3/20 0.45
HRH1 P35367 3/20 0.45
HRH3 Q9Y5N1 2/20 0.45
SIGMAR1 Q99720 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 3/20 0.40
MAPT P10636 1/20 0.40
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10927121 0.94 CXCR4 (0.52) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL20332793 0.92 MEN1 (0.46) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL23657274 0.92 CXCR4 (0.63) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL22266289 0.92 CXCR4 (0.55) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL8321073 0.92 CXCR4 (0.55) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL20332962 0.88 CXCR4 (0.47) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL20332939 0.88 MEN1 (0.46) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL22266300 0.88 MEN1 (0.46) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL92630 0.86 MEN1 (0.54) MEN1KMT2ACXCR4HRH2HRH1
SCHEMBL1476930 0.86 MEN1 (0.54) MEN1KMT2ACXCR4HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114806414-B Silicon polishing composition, preparation method and application thereof 万华化学集团电子材料有限公司 2023-07-11 CN claimed
CN-114806414-A Silicon polishing composition, preparation method and application thereof 万华化学集团电子材料有限公司 2022-07-29 CN claimed
CN-109563092-A It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative 坎塞拉有限公司 2019-04-02 CN claimed
CN-104507950-B Thienopyrimidines 拜耳医药股份有限公司 2017-03-22 CN claimed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
EP-0154669-A1 Catalyst for urethane foam blown with carboxylic acids ABBOTT LABORATORIES (US) 1985-09-18 EP claimed
US-4500654-A N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1985-02-19 US claimed
US-4473666-A A DIALKYLCYCLOHEXYLAMINE AND AN N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1984-09-25 US claimed
WO-2024054953-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-03-14 WO disclosed
EP-4223761-A1 QUINAZOLINE COMPOUND AND APPLICATION THEREOF Shanghai Pharmaceuticals Holding Co., Ltd. (CN) 2023-08-09 EP disclosed
CN-114806414-B Silicon polishing composition, preparation method and application thereof 万华化学集团电子材料有限公司 2023-07-11 CN disclosed
EP-3601297-B9 COMPOUNDS THAT INHIBIT MCL-1 PROTEIN AMGEN INC (US) 2023-05-24 EP disclosed
EP-0154669-A1 Catalyst for urethane foam blown with carboxylic acids ABBOTT LABORATORIES (US) 1985-09-18 EP disclosed
EP-0144573-A2 Catalyst system for the production of polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-06-19 EP disclosed
US-4500654-A N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1985-02-19 US disclosed
US-4473666-A A DIALKYLCYCLOHEXYLAMINE AND AN N-SUBSTITUTED ALKOXYALKYL PIPERAZINE ABBOTT LABORATORIES (US) 1984-09-25 US disclosed
US-4028348-A 6-Amino-5β,19-cycloandrostane derivatives RICHTER GEDEON VEGYESZETI GYAR RT (HU) 1977-06-07 US disclosed