Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.55 |
| ▸ | GPR88 | Q9GZN0 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842741 | 1.00 | MME (0.55) | MMEGPR88MEN1KMT2ANPY1R | |
| SCHEMBL11904819 | 0.83 | MME (0.57) | MMEGPR88MEN1KMT2A | |
| SCHEMBL16050234 | 0.81 | NPY1R (0.48) | MMEGPR88NPY1R | |
| SCHEMBL5285091 | 0.80 | ECE1 (0.52) | MMEGPR88 | |
| SCHEMBL7374278 | 0.78 | MME (0.71) | MMEGPR88 | |
| SCHEMBL5283204 | 0.78 | KMT2A (0.56) | MMEGPR88KMT2A | |
| SCHEMBL17161710 | 0.78 | MEN1 (0.53) | MMEMEN1KMT2A | |
| SCHEMBL6138235 | 0.78 | MME (0.56) | MMEGPR88 | |
| SCHEMBL11196738 | 0.76 | GPR88 (0.50) | GPR88MEN1KMT2A | |
| SCHEMBL8016181 | 0.76 | GPR88 (0.53) | MMEGPR88MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | claimed |