Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874693 | 0.87 | SMN1; SMN2 (0.48) | F2F10MAPTUSP2ALDH1A1 | |
| SCHEMBL6612409 | 0.83 | CHEK2 (0.42) | PARP1MAPTCHEK2PARP10USP2 | |
| SCHEMBL4252143 | 0.76 | PARP1 (0.57) | PARP1FYNMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL893991 | 0.76 | PARP1 (0.57) | PARP1FYNMAPTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3862436 | 0.74 | PARP1 (0.55) | PARP1FYNMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15387056 | 0.73 | PARP1 (0.53) | PARP1FYNMAPTPARP15PARP10 | |
| SCHEMBL2423178 | 0.72 | NPC1 (0.50) | MAPTUSP2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9448353 | 0.72 | PARP1 (0.45) | PARP1F2F10FYNMAPT | |
| SCHEMBL3106119 | 0.71 | PARP1 (0.52) | PARP1FYNMAPTPARP15PARP10 | |
| SCHEMBL26402675 | 0.71 | PARP1 (0.52) | PARP1FYNMAPTPARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | disclosed |