Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893991 | 0.77 | PARP1 (0.57) | PARP1KMT2AFYNSMN1; SMN2MAPT | |
| SCHEMBL4252143 | 0.77 | PARP1 (0.57) | PARP1KMT2AFYNSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3862436 | 0.75 | PARP1 (0.55) | PARP1KMT2AFYNSMN1; SMN2MAPT | |
| SCHEMBL15387056 | 0.74 | PARP1 (0.53) | PARP1KMT2AFYNMAPTPARP15 | |
| SCHEMBL26402675 | 0.72 | PARP1 (0.52) | PARP1KMT2AFYNMAPTPARP15 | |
| SCHEMBL3106119 | 0.72 | PARP1 (0.52) | PARP1FYNMAPTPARP15PARP10 | |
| SCHEMBL27771979 | 0.72 | EGFR (0.39) | KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5842819 | 0.72 | PARP1 (0.47) | PARP1FYNSMN1; SMN2MAPTPARP15 | |
| SCHEMBL3110681 | 0.71 | PARP1 (0.50) | PARP1KMT2AFYNMAPTPARP15 | |
| SCHEMBL3103043 | 0.71 | PARP1 (0.50) | PARP1KMT2AFYNMAPTPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215738-A | Used for destroying hypoxic tumor cells | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | disclosed |