Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842894 | 0.87 | PTPN1 (0.40) | PTPN1GSK3BPDK2ALDH1A1HDAC6 | |
| SCHEMBL5842898 | 0.82 | PTPN1 (0.36) | PTPN1GSK3BSLC16A3SLC16A1PDK2 | |
| SCHEMBL5841349 | 0.81 | PDK2 (0.39) | SLC16A3SLC16A1PDK2ALDH1A1APEX1 | |
| SCHEMBL19829863 | 0.78 | PDK2 (0.33) | SLC16A3SLC16A1PDK2ALDH1A1 | |
| SCHEMBL20856011 | 0.78 | PDK2 (0.38) | PDK2ALDH1A1APEX1SMN1; SMN2 | |
| SCHEMBL30272669 | 0.78 | PDK2 (0.38) | PDK2ALDH1A1APEX1SMN1; SMN2 | |
| SCHEMBL25132561 | 0.74 | HDAC6 (0.33) | PDK2ALDH1A1HPGDHDAC6 | |
| SCHEMBL3793042 | 0.73 | PDK2 (0.40) | PDK2ALDH1A1RAB9AHDAC6SMN1; SMN2 | |
| SCHEMBL30534206 | 0.72 | PDK2 (0.46) | PDK2ALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL5842911 | 0.72 | PTPN1 (0.34) | PTPN1GSK3BPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132572-B2 | Fullerene compounds | Chiang, Long Y. (US) | 2006-11-07 | — | — | US | disclosed |
| US-20050191229-A1 | Fullerene compounds | CHIANG, LONG Y. | 2005-09-01 | — | — | US | disclosed |
| WO-2004007426-A1 | FULLERENE COMPOUNDS | CHIANG LONG Y (US) | 2004-01-22 | — | — | WO | disclosed |