Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842902 | 0.87 | PTPN1 (0.36) | PTPN1GSK3BPDK2HDAC6ALDH1A1 | |
| SCHEMBL5842898 | 0.85 | PTPN1 (0.36) | PTPN1GSK3BPDK2PPARGMEN1 | |
| SCHEMBL30534206 | 0.85 | PDK2 (0.46) | PDK2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3793042 | 0.83 | PDK2 (0.40) | PDK2HDAC6KDM4EALDH1A1MAPT | |
| SCHEMBL5841679 | 0.79 | PDK2 (0.43) | PDK2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1452454 | 0.78 | PDK2 (0.37) | PDK2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25671262 | 0.76 | PDK2 (0.38) | PDK2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13914895 | 0.76 | PDK2 (0.36) | PDK2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1453100 | 0.76 | PDK2 (0.36) | PDK2KDM4EALDH1A1MAPT | |
| SCHEMBL17678560 | 0.75 | PDK2 (0.42) | PDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132572-B2 | Fullerene compounds | Chiang, Long Y. (US) | 2006-11-07 | — | — | US | disclosed |
| US-20050191229-A1 | Fullerene compounds | CHIANG, LONG Y. | 2005-09-01 | — | — | US | disclosed |
| WO-2004007426-A1 | FULLERENE COMPOUNDS | CHIANG LONG Y (US) | 2004-01-22 | — | — | WO | disclosed |