Methacrylic Acid

Methacrylic Acid

SCHEMBL5843019

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.44
TGFBR1 P36897 1/20 0.41
TSHR P16473 2/20 0.40
FFAR3 O14843 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
TP53 P04637 1/20 0.39
ALDH1A1 P00352 2/20 0.38
SLC7A5 Q01650 1/20 0.38
LMNA P02545 2/20 0.33
HSD17B10 Q99714 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
MAPT P10636 1/20 0.32
XBP1 P17861 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TET2 Q6N021 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5841754 1.00 TDP1 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL2377019 1.00 TDP1 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL28997395 0.97 TDP1 (0.42) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL3171234 0.93
Methacrylic Acid SCHEMBL538064 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL10976509 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL733170 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL3665326 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL3642988 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL5196922 0.90 TP53 (0.44) TDP1TGFBR1TSHRFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7135589-B2 Monomers for composite resins with acrylates for unsaturated derivative blends with acids, esters for derivatives with low shrinkage BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-11-14 US disclosed
US-7094358-B2 Ultra-low shrinkage composite resins based on blended nematic liquid crystal monomers THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-08-22 US disclosed
EP-1373184-B1 ULTRA-LOW SHRINKAGE COMPOSITE RESINS BASED ON BLENDED NEMATIC LIQUID CRYSTAL MONOMERS UNIV TEXAS (US) 2005-12-07 EP disclosed
EP-1373184-A4 ULTRA-LOW SHRINKAGE COMPOSITE RESINS BASED ON BLENDED NEMATIC LIQUID CRYSTAL MONOMERS UNIV TEXAS (US) 2005-02-02 EP disclosed
US-20040206934-A1 Ultra-low shrinkage composite resins based on blended nematic liquid crystal secondary monomers BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2004-10-21 US disclosed
EP-1373184-A2 ULTRA-LOW SHRINKAGE COMPOSITE RESINS BASED ON BLENDED NEMATIC LIQUID CRYSTAL MONOMERS THE UNIVERSITY OF TEXAS SYSTEM (US) 2004-01-02 EP disclosed
US-20030125435-A1 Ultra-low shrinkage composite resins based on blended nematic liquid crystal monomers NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-03 US disclosed
WO-2002070543-A2 ULTRA-LOW SHRINKAGE COMPOSITE RESINS BASED ON BLENDED NEMATIC LIQUID CRYSTAL MONOMERS UNIVERSITY OF TEXAS SYSTEM (US) 2002-09-12 WO disclosed