Methacrylic Acid

Methacrylic Acid

SCHEMBL733170

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(C)O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 1/20 0.39
FFAR3 O14843 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
SLC7A5 Q01650 1/20 0.36
TET2 Q6N021 3/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
HPGD P15428 1/20 0.34
TGFBR1 P36897 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5196922 1.00 TP53 (0.44) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL3642988 1.00 TP53 (0.44) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL10976509 1.00 TP53 (0.44) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL28037709 0.97 TP53 (0.42) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL3771205 0.97 TP53 (0.42) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL29723013 0.97 TP53 (0.42) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL11133906 0.94 HPGD (0.41) TP53TDP1ALDH1A1LMNATSHR
Methacrylic Acid SCHEMBL538064 0.93 TP53 (0.44) TP53TDP1ALDH1A1TSHRFFAR3
Methacrylic Acid SCHEMBL3665326 0.93 TP53 (0.44) TP53TDP1ALDH1A1TSHRFFAR3
Methacrylic Acid SCHEMBL18140661 0.90 TP53 (0.42) TP53TDP1ALDH1A1TSHRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3338756-B1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2020-02-26 EP claimed
EP-2716276-B1 Kit and method for indirect chair-side production of composite inlays VOCO GMBH (DE) 2019-04-24 EP claimed
EP-3338756-A1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GmbH (DE) 2018-06-27 EP claimed
EP-2374444-B1 Dental covering material VOCO GMBH (DE) 2017-03-01 EP claimed
EP-2698142-B1 Dental filling materials and dental varnish for the inhibition of biofilm formation of streptococcus mutans, and their preparation VOCO GMBH (DE) 2017-02-01 EP claimed
US-9326917-B2 Dental masking compound VOCO GMBH (DE) 2016-05-03 US claimed
US-9320682-B2 Tooth filling materials and dental varnish for inhibiting the formation of a biofilm of Streptococcus mutans and the production thereof VOCO GMBH (DE) 2016-04-26 US claimed
EP-2374445-B1 Dual hardening multi-component dental composition VOCO GMBH (DE) 2015-07-29 EP claimed
US-20140051036-A1 TOOTH FILLING MATERIALS AND DENTAL VARNISH FOR INHIBITING THE FORMATION OF A BIOFILM OF STREPTOCOCCUS MUTANS AND THE PRODUCTION THEREOF HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) 2014-02-20 US claimed
EP-2698142-A2 Dental filling materials and dental varnish for the inhibition of biofilm formation of streptococcus mutans, and their preparation VOCO GmbH (DE) 2014-02-19 EP claimed
US-8501834-B2 Dual-curing, multi-component dental composition VOCO GMBH (DE) 2013-08-06 US claimed
US-20120093741-A1 DENTAL MASKING COMPOUND VOCO GMBH (DE) 2012-04-19 US claimed
US-20110250558-A1 DUAL-CURING, MULTI-COMPONENT DENTAL COMPOSITION VOCO GMBH (DE) 2011-10-13 US claimed
EP-2374445-A2 Dual hardening multi-component dental composition VOCO GmbH (DE) 2011-10-12 EP claimed
EP-2374444-A2 Dental covering material VOCO GmbH (DE) 2011-10-12 EP claimed
EP-1133971-B1 Cationically polymerizable adhesive composition UNIV MISSOURI (US) 2005-11-30 EP claimed
EP-3011949-B1 CURABLE DENTAL MATERIAL VOCO GMBH (DE) 2021-05-05 EP disclosed
EP-3338756-B1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2020-02-26 EP disclosed
US-5913840-A Soft orthopedic casting article with reinforcement system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-22 US disclosed
US-5167729-A Suitable for automobiles; nonpolluting; corrosion resistance NIPPONDENSO CO., LTD. (JP) 1992-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140051036-A1 TOOTH FILLING MATERIALS AND DENTAL VARNISH FOR INHIBITING THE FORMATION OF A BIOFILM OF STREPTOCOCCUS MUTANS AND THE PRODUCTION THEREOF SRM, SMS, GMPS TP53 2232/4885TDP1 2443/4885ALDH1A1 2717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.