Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.55 |
| ▸ | PTPRB | P23467 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRE | P23469 | 1/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208795 | 0.90 | PTPN1 (0.59) | PTPN1PTPN2PTPRBPTPRCPTPRE | |
| SCHEMBL5837045 | 0.84 | PTPN1 (0.52) | PTPN1PTPN2PTPRBPTPRCPTPRE | |
| SCHEMBL5837077 | 0.80 | PTPN1 (0.48) | PTPN1PTPN2PTPRBKDM4ETP53 | |
| SCHEMBL5837083 | 0.79 | PTPN1 (0.49) | PTPN1PTPN2PTPRBKDM4EPTPRC | |
| SCHEMBL5837588 | 0.79 | PTPN1 (0.54) | PTPN1PTPN2PTPRBPTPRCPTPRE | |
| SCHEMBL5837494 | 0.79 | PTPN1 (0.49) | PTPN1PTPN2PTPRBPTPRCPTPRE | |
| SCHEMBL5838411 | 0.79 | PTPN1 (0.57) | PTPN1PTPN2PTPRBKDM4ESMN1; SMN2 | |
| SCHEMBL5837671 | 0.78 | PTPN1 (0.49) | PTPN1PTPN2PTPRBPTPRCPTPRE | |
| SCHEMBL5838480 | 0.77 | PTPN1 (0.62) | PTPN1PTPN2PTPRBTP53SMN1; SMN2 | |
| SCHEMBL5838028 | 0.77 | PTPN1 (0.63) | PTPN1PTPN2PTPRBPTPRCPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019026-B1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2006-03-28 | — | — | US | claimed |
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | claimed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | claimed |
| US-7019026-B1 | Modulators of Protein Tyrosine Phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2006-03-28 | — | — | US | disclosed |
| EP-1214325-B1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK AS (DK) | 2005-11-09 | — | — | EP | disclosed |