Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30313807 | 0.89 | ALOX15 (0.94) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL20945278 | 0.89 | ALOX15 (0.94) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL105866 | 0.86 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL29365557 | 0.86 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL29549758 | 0.86 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL23924225 | 0.86 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| SCHEMBL5845324 | 0.85 | ALOX15 (0.71) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| Methane SCHEMBL3324869 | 0.84 | CYP3A4 (0.94) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8646655 | 0.84 | CYP3A4 (0.94) | ALOX15HSD17B10CYP3A4MEN1KMT2A | |
| Water SCHEMBL7721550 | 0.84 | CYP3A4 (0.94) | ALOX15HSD17B10CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | claimed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | claimed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | claimed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | claimed |
| CN-115124485-B | Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-115124485-A | Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof | 中国医学科学院药物研究所 | 2022-09-30 | — | — | CN | disclosed |
| EP-3143009-B1 | SUBSTITUTED BENZOXAZOLONE DERIVATIVES AS ACID CERAMIDASE INHIBITORS, AND THEIR USE AS MEDICAMENTS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2019-09-18 | — | — | EP | disclosed |
| US-7122061-B2 | Agents for dyeing keratin fibers, containing 4-aminobiphenyl-3-ol-derivatives | WELLA AG (DE) | 2006-10-17 | — | — | US | disclosed |
| EP-1562539-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| WO-2004041226-A1 | AGENTS FOR DYEING KERATIN FIBERS, CONTAINING 4-AMINO-BIPHENYL-3-OL-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050155160-A1 | Agents for dyeing keratin fibers, containing 4-amino-biphenyl-3-ol-derivatives | KRT18, CBR3, CCNB3 | ALOX15 3006/4885HSD17B10 913/4885CYP3A4 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.