⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2532049 | 0.89 | HDAC3 (0.31) | — | |
| SCHEMBL584240 | 0.86 | STAT3 (0.33) | — | |
| SCHEMBL583982 | 0.86 | STAT3 (0.33) | — | |
| SCHEMBL585456 | 0.85 | CALML3 (0.32) | — | |
| SCHEMBL2529956 | 0.85 | CALML3 (0.32) | — | |
| SCHEMBL714008 | 0.84 | KDM4E (0.37) | — | |
| SCHEMBL2529959 | 0.84 | GSK3B (0.32) | — | |
| SCHEMBL2529958 | 0.84 | KDM4E (0.35) | — | |
| SCHEMBL2526650 | 0.82 | STAT3 (0.33) | — | |
| SCHEMBL2849410 | 0.80 | MAOA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102217-B1 | 4- (2-OXO-OXAZOLIDIN-3YL)-PHENOXYMETHYLE DERIVATIVEAS AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-15 | — | — | EP | disclosed |
| US-8039466-B2 | 5-hydroxymethyl-oxazolidin-2-one antibacterials | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-10-18 | — | — | US | disclosed |
| US-20100069376-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE ANTIBACTERIALS | ACTELION PHARMACEUTICALS, LTD. (CH) | 2010-03-18 | — | — | US | disclosed |