Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035425 | 0.86 | TSHR (0.51) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL8965470 | 0.84 | TSHR (0.62) | TSHRTHRBALDH1A1 | |
| SCHEMBL22554422 | 0.83 | TSHR (0.61) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL4464394 | 0.81 | TSHR (0.53) | TSHRTHRBALDH1A1HPGDTP53 | |
| Acrylic Acid Methyl Ester SCHEMBL28826459 | 0.81 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL11667567 | 0.81 | TSHR (0.53) | TSHRTHRBALDH1A1HPGDTP53 | |
| Acrylic Acid SCHEMBL28165210 | 0.79 | TSHR (0.56) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL700973 | 0.79 | TSHR (0.50) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL8966000 | 0.78 | TSHR (0.75) | TSHRTHRBALDH1A1 | |
| SCHEMBL30633432 | 0.78 | TSHR (0.54) | TSHRTHRBALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101942-B2 | Dental materials based on metal oxide clusters | IVOCLAR VIVADENT AG (LI) | 2006-09-05 | — | — | US | disclosed |
| US-20030004294-A1 | Dental materials based on metal oxide clusters | IVOCLAR VIVADENT AG (LI) | 2003-01-02 | — | — | US | disclosed |
| US-5547762-A | THERMOSETTING RESIN LAYER | BRIDGESTONE CORPORATION (JP) | 1996-08-20 | — | — | US | disclosed |