Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700973 | 0.97 | TSHR (0.50) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL10798610 | 0.94 | TSHR (0.47) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL282920 | 0.92 | TSHR (0.49) | TSHRPRKCA | |
| SCHEMBL8853542 | 0.90 | TSHR (0.47) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL176350 | 0.90 | TSHR (0.50) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL28027569 | 0.89 | TSHR (0.46) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL18567468 | 0.88 | TSHR (0.49) | TSHRTHRBALDH1A1HPGDTP53 | |
| SCHEMBL28745471 | 0.88 | TSHR (0.45) | TSHRTHRBALDH1A1HPGDPRKCA | |
| SCHEMBL20148972 | 0.87 | TSHR (0.41) | TSHRALDH1A1PRKCA | |
| SCHEMBL15397841 | 0.86 | TSHR (0.44) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102225945-B | A kind of (methyl) vinylformic acid esterification oxazole heterocyclic boronic acids ester and its preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2015-08-19 | — | — | CN | claimed |
| EP-3328871-B1 | CROSSLINKING MONOMERS WITH AT LEAST ONE ATOM OF SULPHUR | KULZER & CO GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| US-20190010174-A1 | Crosslinking Monomers With at Least One Sulfur Atom | KULZER GMBH (DE) | 2019-01-10 | — | — | US | disclosed |
| EP-3328871-A1 | CROSSLINKING MONOMERS WITH AT LEAST ONE ATOM OF SULPHUR | Kulzer GmbH (DE) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017021297-A1 | CROSSLINKING MONOMERS WITH AT LEAST ONE ATOM OF SULPHUR | HERAEUS KULZER GMBH (DE) | 2017-02-09 | — | — | WO | disclosed |
| WO-2017021297-A1 | CROSSLINKING MONOMERS WITH AT LEAST ONE ATOM OF SULPHUR | HERAEUS KULZER GMBH (DE) | 2017-02-09 | — | — | WO | disclosed |
| EP-1510197-B1 | Dental coating material | IVOCLAR VIVADENT AG (LI) | 2016-03-09 | — | — | EP | disclosed |
| CN-102225945-B | A kind of (methyl) vinylformic acid esterification oxazole heterocyclic boronic acids ester and its preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-102667531-B | Black curable composition for wafer level lens and wafer level lens | FUJIFILM CORP | 2015-03-04 | — | — | CN | disclosed |
| CN-102667531-A | Black curable composition for wafer level lens and wafer level lens | FUJIFILM CORP | 2012-09-12 | — | — | CN | disclosed |
| US-7932414-B2 | Silane and silicic acid polycondensates with radicals containing branched-chain urethane, acid amide and/or carboxylic acid ester groups | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2011-04-26 | — | — | US | disclosed |
| US-7495037-B2 | Dental coating materials | IVOCLAR VIVADENT AG (LI) | 2009-02-24 | — | — | US | disclosed |
| US-20070135572-A1 | Silane and silicic acid polycondensates with radicals containing branched-chain urethane, acid amide and/or carboxylic acid ester groups | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. | 2007-06-14 | — | — | US | disclosed |
| US-20050165129-A1 | Dental coating materials | IVOCLAR VIVADENT AG (LI) | 2005-07-28 | — | — | US | disclosed |
| EP-1510197-A1 | Dental coating material | Firma Ivoclar Vivadent AG (LI) | 2005-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190010174-A1 | Crosslinking Monomers With at Least One Sulfur Atom | H1-3, H1-0, H1-4 | TSHR 1392/4885THRB 2141/4885ALDH1A1 2069/4885 |
| US-20050165129-A1 | Dental coating materials | PHOSPHO1, SPTAN1, ITGA1 | TSHR 4370/4885THRB 3247/4885ALDH1A1 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.