Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842215 | 0.83 | CA2 (0.46) | ALDH1A1GAAHPGDKMT2ACA2 | |
| SCHEMBL5843449 | 0.80 | KMT2A (0.60) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL4113212 | 0.78 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL1096091 | 0.76 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL5844286 | 0.75 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL17076648 | 0.75 | CA1 (0.46) | ALDH1A1GAAGFERCA12CA2 | |
| SCHEMBL4765888 | 0.75 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL23665692 | 0.73 | CYP4F2 (0.54) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL23647680 | 0.73 | SMN1; SMN2 (0.59) | CYP4F2CYP4A11ALDH1A1HPGDMAPT | |
| SCHEMBL980066 | 0.73 | CYP4F2 (0.54) | CYP4F2CYP4A11ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992193-B2 | Sulfonylamino phenylacetamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2006-01-31 | — | — | US | disclosed |
| US-20040254156-A1 | Sulfonylamino phenylacetamide derivatives and methods of their use | CALIXA THERAPEUTICS, INC. | 2004-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254156-A1 | Sulfonylamino phenylacetamide derivatives and methods of their use | CYP2E1, CYP2D6, CYP3A43 | CYP4F2 44/4885CYP4A11 49/4885ALDH1A1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.