Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719141 | 0.85 | DPP4 (0.55) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL27469192 | 0.76 | DPP4 (0.46) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL3831522 | 0.76 | DPP4 (0.46) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL9567852 | 0.76 | DPP4 (0.46) | DPP4F2HTR2ATAAR1ADRA2A | |
| Aminodiphenylmethane SCHEMBL7841 | 0.76 | DPP4 (0.65) | DPP4F2HTR2ATAAR1ADRA2A | |
| SCHEMBL21380575 | 0.75 | SLC6A2 (0.42) | DPP4F2HTR2ATAAR1 | |
| SCHEMBL4879178 | 0.75 | SLC6A2 (0.42) | DPP4F2 | |
| SCHEMBL3999911 | 0.74 | IDO1 (0.55) | DPP4F2 | |
| SCHEMBL22570757 | 0.74 | IDO1 (0.57) | DPP4F2ADRA2ALMNAHIF1A | |
| SCHEMBL17871730 | 0.74 | IDO1 (0.55) | DPP4F2HTR2ATAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984716-B2 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2006-01-10 | — | — | US | disclosed |
| US-20040077825-A1 | Phosphorus-containing compound | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-22 | — | — | US | disclosed |
| US-6566385-B2 | And the prenylation of the oncogene protein Ras; peptidomimetic macrocyclic compounds | MERCK & CO., INC. | 2003-05-20 | — | — | US | disclosed |
| US-20020099007-A1 | Inhibitors of prenyl-protein transferase | MERCK SHARP & DOHME CORP. | 2002-07-25 | — | — | US | disclosed |
| WO-2001051127-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099007-A1 | Inhibitors of prenyl-protein transferase | FNTA, KRAS, NRAS | DPP4 2297/4885F2 3148/4885HTR2A 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.