Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831522 | 1.00 | DPP4 (0.46) | DPP4F2CYP3A4ALOX15CASP1 | |
| SCHEMBL9567852 | 1.00 | DPP4 (0.46) | DPP4F2CYP3A4ALOX15CASP1 | |
| SCHEMBL17253900 | 0.87 | CA1 (0.45) | CYP3A4ALOX15SMN1; SMN2LMNAMAPT | |
| Cadaverine Tartrate SCHEMBL9567867 | 0.85 | LMNA (0.42) | CYP2D6LMNAADRA2AADRA2C | |
| Cadaverine Tartrate SCHEMBL9567868 | 0.85 | LMNA (0.42) | CYP2D6LMNAADRA2AADRA2C | |
| SCHEMBL11774848 | 0.85 | CYP3A4 (0.50) | DPP4F2CYP3A4ALOX15CASP1 | |
| SCHEMBL9719141 | 0.85 | DPP4 (0.55) | DPP4F2LMNAHTR2ATAAR1 | |
| SCHEMBL17253774 | 0.82 | MAOA (0.44) | DPP4F2CYP3A4ALOX15LMNA | |
| SCHEMBL11131221 | 0.80 | DPP4 (0.41) | DPP4F2LMNAADRA2AADRA2C | |
| SCHEMBL17454868 | 0.78 | GAA (0.41) | CYP3A4ALOX15SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1076445-A | The phenylquinazoline derivates that replaces | SANDOZ LTD (US) | 1993-09-22 | — | — | CN | disclosed |