SCHEMBL58443

SCHEMBL58443

O=[N+]([O-])c1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.72
GAA P10253 1/20 0.72
HTT P42858 1/20 0.72
CA2 P00918 3/20 0.68
CA5A P35218 1/20 0.68
MMP2 P08253 2/20 0.62
CA1 P00915 1/20 0.62
MMP1 P03956 1/20 0.62
MMP9 P14780 1/20 0.62
MMP8 P22894 1/20 0.62
MMP13 P45452 1/20 0.62
MEN1 O00255 2/20 0.60
LMNA P02545 2/20 0.59
TSHR P16473 1/20 0.59
F2 P00734 2/20 0.57
PRSS1 P07477 2/20 0.57
PRSS2 P07478 2/20 0.57
PRSS3 P35030 2/20 0.57
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7569229 0.98 KMT2A (0.70) KMT2AGAAHTTCA2CA5A
Hydrochloric Acid SCHEMBL7569226 0.98 KMT2A (0.70) KMT2AGAAHTTCA2CA5A
SCHEMBL9143049 0.95 KMT2A (0.66) KMT2AGAAHTTCA2CA5A
SCHEMBL8592078 0.90 KMT2A (0.60) KMT2AGAAHTTCA2CA5A
SCHEMBL9580710 0.84 KMT2A (1.00) KMT2AGAAHTTCA2CA5A
SCHEMBL8093693 0.84 KMT2A (0.53) KMT2AGAAHTTCA2CA5A
SCHEMBL27930192 0.84 KMT2A (0.66) KMT2AGAAHTTCA2CA5A
Dinitrophenylene SCHEMBL8975758 0.84 TSHR (0.77) KMT2AGAAHTTCA2CA5A
SCHEMBL205255 0.82 KMT2A (0.75) KMT2AGAAHTTCA2CA5A
SCHEMBL12570988 0.82 GAA (0.54) KMT2AGAAHTTCA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2936 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-118754867-A Synthesis method of landiolol hydrochloride 伊诺药物研究(南京)有限公司 2024-10-11 CN claimed
CN-115197107-B Meta-ester chlorosulfonation synthesis method with high yield and low consumption of sulfonating agent 湖北丽康源化工有限公司 2024-07-30 CN claimed
CN-117567396-A Process for preparing S-type glycidol mesylate from R-type 3-chloro-1, 2-propanediol 宁夏坤正生物科技有限公司 2024-02-20 CN claimed
CN-116120261-B Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound 浙大宁波理工学院 2024-01-23 CN claimed
CN-111978242-B Preparation method and application of (R) -3-aminopiperidine dihydrochloride 上海科利生物医药有限公司 2023-09-26 CN claimed
CN-116715593-A Optimized preparation method of dapoxetine hydrochloride and intermediate thereof 北京悦康科创医药科技股份有限公司 2023-09-08 CN claimed
CN-116120261-A Preparation method of 3- [ (4-sulfadiazine-1-yl) methyl ] benzoic acid compound 浙大宁波理工学院 2023-05-16 CN claimed
US-20230021368-A1 PROCESS FOR THE PREPARATION OF CHLORANTRANILIPROLE GHARDA CHEMICALS LIMITED (IN) 2023-01-26 US claimed
EP-1138685-A2 Process for preparing substituted pyridines Pfizer Products Inc. (US) 2001-10-04 EP claimed
EP-0884313-B1 PROCESS FOR PRODUCING GLYCIDYL SULFONATE DERIVATIVES DAISO CO LTD (JP) 2000-11-08 EP claimed
US-5965753-A Process for preparation of glycidyl sulfonate derivative DAISO CO., LTD. (JP) 1999-10-12 US claimed
EP-0576228-B1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates LILLY CO ELI (US) 1999-02-03 EP claimed
EP-0884313-A1 PROCESS FOR PRODUCING GLYCIDYL SULFONATE DERIVATIVES DAISO CO., LTD. (JP) 1998-12-16 EP claimed
US-5436370-A From nitrobenzene, chlorosulfonic acid, thionyl chloride HOECHST AG (DE) 1995-07-25 US claimed
EP-0518875-B1 METHOD FOR PREPARING 3-NITROBENZENE SULPHONIC ACID CHLORIDE HOECHST AG (DE) 1994-09-21 EP claimed
EP-0576228-A1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-12-29 EP claimed
US-5252756-A Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-10-12 US claimed
US-5066801-A PREPARATION OF SULFONIC ACID ESTERS CIBA-GEIGY CORPORATION (US) 1991-11-19 US claimed