Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitrophenylene SCHEMBL28055356 | 0.98 | TSHR (0.74) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL9798067 | 0.91 | TSHR (0.71) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL29291896 | 0.88 | TSHR (1.00) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL36632 | 0.88 | TSHR (1.00) | TSHRLMNAKMT2AGAAHTT | |
| SCHEMBL27285615 | 0.88 | ALDH1A1 (0.85) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL34066 | 0.86 | TSHR (0.77) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL27729739 | 0.86 | TSHR (0.77) | TSHRLMNAKMT2AGAAHTT | |
| Dinitrophenylene SCHEMBL27624439 | 0.86 | TSHR (0.77) | TSHRLMNAKMT2AGAAHTT | |
| SCHEMBL6543155 | 0.86 | TSHR (0.81) | TSHRLMNAKMT2AGAAHTT | |
| SCHEMBL6597968 | 0.86 | TSHR (0.57) | TSHRLMNAKMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278001-B | Near-infrared selenocysteine fluorescent probe and preparation method and application thereof | 中南大学 | 2024-04-05 | — | — | CN | claimed |
| CN-115894427-B | Near-infrared frequency up-conversion fluorescent probe, preparation method thereof and application thereof in detection of biological mercaptan | 赣南师范大学 | 2024-02-06 | — | — | CN | claimed |
| CN-114539183-B | Lipid-droplet targeting and biological thiol-sensitive fluorescent probe for cancer cell tissue diagnosis and preparation and application thereof | 吉林化工学院 | 2023-07-21 | — | — | CN | claimed |
| CN-113667114-B | SO with main chain capable of being eliminated 2 Preparation method and application of nano prodrug | 北京大学深圳医院 | 2023-07-14 | — | — | CN | claimed |
| CN-115160349-A | Near-infrared fluorescent probe for detecting selenocysteine and preparation method and application thereof | 中国药科大学 | 2022-10-11 | — | — | CN | claimed |
| CN-113292479-B | Preparation method of 5-azaspiro [2.4] heptane and salt thereof | 南京合巨药业有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114539183-A | Lipid drop targeting and biological thiol sensitive fluorescent probe for cancer cell tissue diagnosis, preparation and application | 吉林化工学院 | 2022-05-27 | — | — | CN | claimed |
| WO-2022035405-A1 | A DRUG AND SYNTHESIS OF THE DRUG TO TREAT HIGH BLOOD PRESSURE AND TYPE 2 DIABETES MELLITUS DISEASE | GAZIANTEP UNIVERSITESI REKTORLUGU (TR) | 2022-02-17 | — | — | WO | claimed |
| CN-113943261-A | N-carboxyanhydride, preparation method and application thereof | 中国科学院长春应用化学研究所 | 2022-01-18 | — | — | CN | claimed |
| CN-113880778-A | Method for preparing 6-amino-5-nitroquinoxaline | 安徽皓元药业有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-112745247-A | Novel dye intermediate, novel dye and preparation method thereof | 湖北丽源科技股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-107915705-B | Dithiothreitol fluorescent probe | 济南大学 | 2021-04-30 | — | — | CN | claimed |
| CN-111875561-A | Naphthalene derivative two-photon probe for specifically recognizing selenocysteine and preparation and application thereof | 中南林业科技大学 | 2020-11-03 | — | — | CN | claimed |
| CN-107823184-B | Preparation method and application of redox sensitive induced pH response nano-drug carrier | 中国医学科学院生物医学工程研究所 | 2020-10-23 | — | — | CN | claimed |
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-109678763-B | Near-infrared biological thiol fluorescent probe and preparation method and application thereof | 华南理工大学 | 2020-05-08 | — | — | CN | claimed |
| CN-107721888-B | Oxidation-reduction induced pH response type methacrylate fluorine-containing monomer, and synthesis method and application thereof | 中国医学科学院生物医学工程研究所 | 2020-04-21 | — | — | CN | claimed |
| CN-109678763-A | A kind of near-infrared biological thiol fluorescence probe and its preparation method and application | 华南理工大学 | 2019-04-26 | — | — | CN | claimed |
| CN-104560027-B | A kind of fluorescent probe distinguishing detection biological thiol and preparation method thereof | 中国科学技术大学 | 2016-08-24 | — | — | CN | claimed |
| CN-104370848-A | Method for synthesizing sulfuric ion fluorescent probe with hydroxyl Nile red as parent body and application of sulfuric ion fluorescent probe | UNIV HUNAN SCI & TECHNOLOGY | 2015-02-25 | — | — | CN | claimed |