Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843211 | 0.86 | ABCB1 (0.45) | ABCB1MC4RMC3RMC1RP2RX7 | |
| SCHEMBL5844838 | 0.82 | MC3R (0.53) | MC4RMC3RMC1RF2PRSS1 | |
| SCHEMBL5844741 | 0.78 | ABCB1 (0.57) | ABCB1F2 | |
| SCHEMBL5844739 | 0.78 | ABCB1 (0.57) | ABCB1F2 | |
| SCHEMBL3059318 | 0.75 | ABCB1 (0.47) | ABCB1ACE | |
| SCHEMBL3059316 | 0.75 | ABCB1 (0.47) | ABCB1ACE | |
| SCHEMBL3812802 | 0.73 | ABCB1 (0.46) | ABCB1CTSKCTSL | |
| SCHEMBL3063867 | 0.73 | ABCB1 (0.46) | ABCB1CTSKCTSL | |
| SCHEMBL15047170 | 0.73 | KLK7 (0.49) | CTSSCTSKKMT2AACECTSL | |
| SCHEMBL18813663 | 0.72 | CTSS (0.62) | P2RX7CTSSCTSKACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132539-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-20060247224-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2006-11-02 | — | — | US | disclosed |
| EP-1556361-A2 | 2-ALKYL-(2-AMINO-3-ARYL-PROPIONYL)-PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY | THE PROCTER & GAMBLE COMPANY (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20050010031-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2005-01-13 | — | — | US | disclosed |
| WO-2004037797-A2 | 2 - ALKYL - (2 - AMINO - 3 - ARYL - PROPIONYL) - PIPERAZINE DERIVATIVES AND RELATED COMPOUNDS AS MELANOCORTIN RECEPTOR LIGANDS FOR THE TREATMENT OF OBESITY | THE PROCTER & GAMBLE COMPANY (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010031-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | PABPC1 3834/4885ABCB1 3595/4885MC4R 8/4885 |
| US-20060247224-A1 | Melanocortin receptor ligands | MC3R, MC5R, MC1R | PABPC1 3855/4885ABCB1 3470/4885MC4R 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.