Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CCR8 | P51685 | 3/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353368 | 0.85 | MEN1 (0.52) | GRM5LMNAHTTTGFBR1KDM4E | |
| SCHEMBL514547 | 0.85 | MEN1 (0.52) | GRM5LMNAHTTTGFBR1KDM4E | |
| SCHEMBL29352118 | 0.85 | MEN1 (0.52) | GRM5LMNAHTTTGFBR1KDM4E | |
| SCHEMBL2692720 | 0.83 | GRM5 (0.54) | GRM5LMNAHTTTGFBR1KDM4E | |
| SCHEMBL4404741 | 0.83 | GRM5 (0.51) | GRM5LMNAHTTTGFBR1KDM4E | |
| SCHEMBL1518061 | 0.83 | MEN1 (0.51) | GRM5LMNATGFBR1KDM4ECCR1 | |
| SCHEMBL31036229 | 0.83 | MEN1 (0.51) | GRM5LMNATGFBR1KDM4ECCR1 | |
| SCHEMBL31549509 | 0.83 | MEN1 (0.51) | GRM5LMNATGFBR1KDM4ECCR1 | |
| SCHEMBL30958581 | 0.83 | MEN1 (0.51) | GRM5LMNATGFBR1KDM4ECCR1 | |
| SCHEMBL7166636 | 0.83 | MEN1 (0.51) | GRM5LMNATGFBR1KDM4ECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129044-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2025-04-24 | — | — | US | disclosed |
| US-20230150972-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-05-18 | — | — | US | disclosed |
| CN-107207514-B | Fused heteroaryl compounds and their use as TRK inhibitors | 康联制药有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-103193568-B | The selective hydrogenation reduction method of fluorine-containing arene derivatives | 中国科学院上海有机化学研究所 | 2017-11-07 | — | — | CN | disclosed |
| CN-103193568-A | Selective hydrogenation reduction method of fluorine-containing aromatic hydrocarbon derivative | SHANGHAI INST ORGANIC CHEM | 2013-07-10 | — | — | CN | disclosed |
| CN-1325503-C | Luminous organic intermetallic compound and luminous element | SANYO ELECTRIC CO (JP) | 2007-07-11 | — | — | CN | disclosed |
| US-7067202-B2 | Luminous efficiency and capable of emitting light of spectrum components of red or blue wavelength band; for use in organic electroluminescent device | SANYO ELECTRIC CO., LTD. (JP) | 2006-06-27 | — | — | US | disclosed |
| US-20030040627-A1 | Luminescent organometallic compound and light emitting device | SANYO ELECTRIC CO., LTD. (JP) | 2003-02-27 | — | — | US | disclosed |
| CN-1397559-A | Luminous organic intermetallic compound and luminous element | SANYO ELECTRIC CO (JP) | 2003-02-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129044-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | SCN1B, SCN1A, SCN2B | GRM5 636/4885LMNA 287/4885HTT 4258/4885 |
| US-20030040627-A1 | Luminescent organometallic compound and light emitting device | IK, CRY1, LBR | GRM5 1398/4885LMNA 3413/4885HTT 3340/4885 |
| US-20230150972-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | SCN1B, SCN1A, SCN2B | GRM5 636/4885LMNA 287/4885HTT 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.