SCHEMBL5845757

SCHEMBL5845757

O=C(c1ccccc1)c1ccc(Oc2ccc(O)cc2)cc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
USP2 O75604 1/20 0.70
GAA P10253 1/20 0.70
KEAP1 Q14145 1/20 0.70
NFE2L2 Q16236 1/20 0.70
HPGD P15428 4/20 0.69
LMNA P02545 4/20 0.69
CYP1A2 P05177 2/20 0.69
PGR P06401 2/20 0.69
SLC6A2 P23975 2/20 0.69
CYP2C19 P33261 2/20 0.69
MAPK1 P28482 2/20 0.69
ALDH1A1 P00352 1/20 0.69
CYP2D6 P10635 1/20 0.69
PDE4A P27815 1/20 0.69
HRH1 P35367 1/20 0.69
HTT P42858 1/20 0.69
SLC6A3 Q01959 1/20 0.69
PDE4D Q08499 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337469 0.95 HPGD (0.71) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL5384205 0.91 HPGD (0.66) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL5846470 0.89 HPGD (0.64) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL10883695 0.87 HPGD (0.73) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL21275713 0.86 HPGD (0.64) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL9647575 0.83 HPGD (0.83) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL17653993 0.83 HPGD (0.64) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL24421676 0.83 SRD5A2 (0.69) MEN1KMT2AHPGDLMNAALDH1A1
SCHEMBL18401385 0.83 SRD5A2 (0.69) MEN1KMT2AHPGDLMNAALDH1A1
SCHEMBL7938036 0.83 SRD5A2 (0.69) MEN1KMT2AHPGDLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125443-B2 Lightfast colorant and lightfast ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-7125442-B2 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-12-02 US disclosed
US-20040182279-A1 Lightfast colorant and lightfast ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040182279-A1 Lightfast colorant and lightfast ink composition including the same RB1, CDK4, CDKL4 MEN1 3666/4885KMT2A 480/4885USP2 2329/4885
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same CDK4, CDKL4, UGT1A4 MEN1 3693/4885KMT2A 624/4885USP2 1549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.