SCHEMBL5846470

SCHEMBL5846470

Nc1ccc(Oc2ccc(C(=O)c3ccccc3)c(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.64
LMNA P02545 4/20 0.64
SLC6A2 P23975 3/20 0.64
PDE4A P27815 2/20 0.64
SLC6A3 Q01959 2/20 0.64
CYP1A2 P05177 2/20 0.64
PGR P06401 2/20 0.64
CYP2C19 P33261 2/20 0.64
ALDH1A1 P00352 2/20 0.64
CYP2D6 P10635 1/20 0.64
MAPK1 P28482 1/20 0.64
HRH1 P35367 1/20 0.64
HTT P42858 1/20 0.64
PDE4D Q08499 1/20 0.64
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
GAA P10253 2/20 0.59
USP2 O75604 1/20 0.59
KEAP1 Q14145 1/20 0.59
NFE2L2 Q16236 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30092628 0.92 PARP10 (0.54) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL337469 0.91 HPGD (0.71) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL5845757 0.89 MEN1 (0.70) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL5384205 0.87 HPGD (0.66) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL9222768 0.85 POLB (0.56) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL11650147 0.85 POLB (0.59) LMNAALDH1A1MAPK1HTTMEN1
SCHEMBL5384700 0.85 LMNA (0.59) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL30286753 0.84 POLB (0.57) ALDH1A1MEN1KMT2AGAAPOLB
SCHEMBL10883695 0.83 HPGD (0.73) HPGDLMNASLC6A2PDE4ASLC6A3
SCHEMBL3294925 0.83 ALDH1A1 (0.65) HPGDLMNASLC6A2PDE4ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125443-B2 Lightfast colorant and lightfast ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-7125442-B2 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-12-02 US disclosed
US-20040182279-A1 Lightfast colorant and lightfast ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040182279-A1 Lightfast colorant and lightfast ink composition including the same RB1, CDK4, CDKL4 HPGD 1896/4885LMNA 885/4885SLC6A2 3474/4885
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same CDK4, CDKL4, UGT1A4 HPGD 2175/4885LMNA 862/4885SLC6A2 2078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.