SCHEMBL584581

SCHEMBL584581

Clc1ccc2sc(Cc3nc4cc(Cl)ccc4s3)nc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.74
HDAC6 Q9UBN7 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
IDO1 P14902 1/20 0.54
TRPV1 Q8NER1 2/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
DRD2 P14416 3/20 0.45
DRD3 P35462 3/20 0.45
HTR1A P08908 2/20 0.45
HTR2A P28223 2/20 0.45
HTR2C P28335 2/20 0.45
HTR7 P34969 2/20 0.45
HRH1 P35367 2/20 0.45
HTR2B P41595 2/20 0.45
DRD4 P21917 1/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30471048 0.87 LOXL2 (0.72) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL201922 0.87 LOXL2 (0.72) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL2956510 0.87 LOXL2 (0.62) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL30209080 0.85 LOXL2 (1.00) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL7461310 0.85 LOXL2 (0.70) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL9892808 0.85 LOXL2 (0.70) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL3248813 0.85 LOXL2 (1.00) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL21104587 0.85 LOXL2 (0.70) LOXL2HDAC6SMN1; SMN2NPSR1IDO1
SCHEMBL11328940 0.85 NPC1 (0.54) LOXL2HDAC6SMN1; SMN2NPC1RAB9A
SCHEMBL2000214 0.83 LOXL2 (0.61) LOXL2HDAC6SMN1; SMN2NPSR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2417647-B1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC (US) 2014-11-19 EP disclosed
US-8206842-B2 Organic element for electroluminescent devices GLOBAL OLED TECHNOLOGY LLC (US) 2012-06-26 US disclosed
US-8206842-B2 Organic element for electroluminescent devices GLOBAL OLED TECHNOLOGY LLC (US) 2012-06-26 US disclosed
US-8206842-B2 Organic element for electroluminescent devices GLOBAL OLED TECHNOLOGY LLC (US) 2012-06-26 US disclosed
EP-2417647-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES Global OLED Technology LLC (US) 2012-02-15 EP disclosed
WO-2010117886-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC (US) 2010-10-14 WO disclosed
US-20100253210-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC 2010-10-07 US disclosed
US-20100253210-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC 2010-10-07 US disclosed
US-20100253210-A1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC 2010-10-07 US disclosed