Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.55 |
| ▸ | SELP | P16109 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338644 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL5845029 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL2395804 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL4148858 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL5845203 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL4130261 | 1.00 | HMGCR (0.55) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL2393399 | 0.97 | — | — | |
| SCHEMBL6408336 | 0.91 | HMGCR (0.57) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL10777606 | 0.91 | HMGCR (0.57) | HMGCRPTPN7SELPRECQLTDP1 | |
| SCHEMBL953771 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015209-B2 | Hair-growing agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-21 | — | — | US | disclosed |
| US-20040266730-A1 | Hair-growing agent | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1214928-A1 | HAIR GROWTH STIMULANTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-5478862-A | Having progestational activity with minimum ancillary hormonal activity; antiovulation agents | SRI INTERNATIONAL (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0500899-B1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | STANFORD RES INST INT (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5321044-A | Ovulation suppression | SRI INTERNATIONAL (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0500899-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS. | STANFORD RES INST INT (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5116830-A | Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses | SRI INTERNATIONAL (US) | 1992-05-26 | — | — | US | disclosed |
| US-5116865-A | Antifertility Agents | SRI INTERNATIONAL, A CORP OF CA | 1992-05-26 | — | — | US | disclosed |
| WO-1992004309-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | SRI INTERNATIONAL (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0190149-B1 | STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF | SRI INTERNATIONAL (US) | 1989-12-13 | — | — | EP | disclosed |
| US-4788218-A | MALE FERTILITY CONTROL | SRI INTERNATIONAL (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0190149-A1 | STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF. | STANFORD RES INST INT (US) | 1986-08-13 | — | — | EP | disclosed |
| EP-0182808-A1 | 17 a?$g(b)-HYDROXY-7$g(a)-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES | SRI INTERNATIONAL (US) | 1986-06-04 | — | — | EP | disclosed |
| WO-1986001208-A1 | STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF | SRI INTERNATIONAL (US) | 1986-02-27 | — | — | WO | disclosed |
| WO-1985005361-A1 | 17abeta-HYDROXY-7alpha-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES | SRI INTERNATIONAL (US) | 1985-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266730-A1 | Hair-growing agent | PHOSPHO1, LPAR1, LPCAT3 | HMGCR 1036/4885PTPN7 3364/4885SELP 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.