Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643129 | 1.00 | PARP1 (0.54) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL3055056 | 0.98 | PARP1 (0.56) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL3055055 | 0.98 | PARP1 (0.56) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL5846987 | 0.94 | PARP1 (0.51) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL23453361 | 0.89 | PARP1 (0.51) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL23453360 | 0.89 | PARP1 (0.51) | PARP1LMNATSHRNOS1ACHE | |
| SCHEMBL23453325 | 0.87 | LMNA (0.58) | PARP1LMNATSHRACHEBCHE | |
| SCHEMBL23453324 | 0.87 | LMNA (0.58) | PARP1LMNATSHRACHEBCHE | |
| SCHEMBL31199231 | 0.85 | LMNA (0.60) | PARP1LMNATSHRACHEBCHE | |
| SCHEMBL11136858 | 0.85 | LMNA (0.60) | PARP1LMNATSHRACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252895-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | BASELL TECHNOLOGY COMPANY B.V. | 2006-11-09 | — | — | US | disclosed |
| US-7094847-B2 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2006-08-22 | — | — | US | disclosed |
| EP-0702687-B1 | METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2001-12-05 | — | — | EP | disclosed |
| US-20010012877-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY B.V. | 2001-08-09 | — | — | US | disclosed |
| US-6211108-B1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252895-A1 | Metallocene compounds and use thereof in catalysts for the polymerization of olefins | CPNE4, OR10J3, ORC3 | PARP1 108/4885LMNA 3701/4885TSHR 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.