Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494774 | 0.87 | ALDH1A1 (0.52) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL30022761 | 0.87 | ALDH1A1 (0.52) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL673430 | 0.85 | ALDH1A1 (0.59) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL3145785 | 0.79 | GAA (0.40) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL14458138 | 0.78 | GAA (0.56) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL2844043 | 0.78 | ERN1 (0.55) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL1980636 | 0.78 | GAA (0.39) | GAAMAPTKDM4EMCL1ALDH1A1 | |
| SCHEMBL729589 | 0.78 | ALDH1A1 (0.57) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL15538025 | 0.76 | ALDH1A1 (0.52) | GAAMAPTKDM4EALDH1A1TSHR | |
| Formaldehyde SCHEMBL27601449 | 0.75 | KDM4E (0.53) | GAAMAPTKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7001957-B2 | Blending hexamethylene diamine curative agent with an ethylene/alkyl acrylate copolymer containing a monoalkyl ester of a 1,4-butene-dioic acid cure-site termonomer, heating, pressurization to crosslink, heating | E.I. DU PONT DE NEMOURS AND COMPANY, INC. (US) | 2006-02-21 | — | — | US | claimed |
| US-7001957-B2 | Blending hexamethylene diamine curative agent with an ethylene/alkyl acrylate copolymer containing a monoalkyl ester of a 1,4-butene-dioic acid cure-site termonomer, heating, pressurization to crosslink, heating | E.I. DU PONT DE NEMOURS AND COMPANY, INC. (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1499670-B1 | METHOD OF MANUFACTURING CURED ETHYLENE ACRYLIC AND POLYACRYLATE ELASTOMERS | DU PONT (US) | 2005-07-06 | — | — | EP | disclosed |
| US-20030204025-A1 | Blending hexamethylene diamine curative agent with an ethylene/alkyl acrylate copolymer containing a monoalkyl ester of a 1,4-butene-dioic acid cure-site termonomer, heating, pressurization to crosslink, heating | DUPONT POLYMERS, INC. | 2003-10-30 | — | — | US | disclosed |