Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146728 | 1.00 | PDK2 (0.55) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL31151124 | 1.00 | PDK2 (0.55) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL2456262 | 1.00 | PDK2 (0.55) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL5847201 | 1.00 | PDK2 (0.55) | PDK2TTRSRD5A2PTPRCPOLB | |
| Hydrochloric Acid SCHEMBL5846911 | 0.98 | PDK2 (0.54) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL29823550 | 0.92 | PDK2 (0.49) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL29824042 | 0.92 | PDK2 (0.49) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL28874569 | 0.92 | PDK2 (0.49) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL31242361 | 0.91 | PDK2 (0.51) | PDK2TTRSRD5A2PTPRCPOLB | |
| SCHEMBL18419410 | 0.91 | PDK2 (0.51) | PDK2TTRSRD5A2PTPRCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7088757-B1 | Use of spiro compounds as laser dyes | SEMICONDUCTORS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| US-6822094-B2 | AMORPHOUS SPIROBIFLUORENE COMPOUND USED IN A PHOTOVOLTIC CELL AS CHARGE TRANSPORTING MATERIAL | AVENTIS RESEARCH & TECHNOLOGIES, GMBH & CO. KG (DE) | 2004-11-23 | — | — | US | disclosed |
| US-20030111107-A1 | Spiro compounds and their use | MERCK OLED MATERIALS GMBH (DE) | 2003-06-19 | — | — | US | disclosed |
| EP-1053578-B1 | USE OF SPIRO COMPOUNDS AS LASER DYES | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-05-08 | — | — | EP | disclosed |
| US-6187224-B1 | ORGANIC SPIRO COMPOUNDS WHICH COMPRISE A CONJUGATED SYSTEM | AXIVA GMBH (DE) | 2001-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030111107-A1 | Spiro compounds and their use | PKD1, PKD2, REN | PDK2 478/4885TTR 1206/4885SRD5A2 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.