Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834053 | 0.80 | AKR1C3 (0.63) | AKR1C3AKR1C2ALDH1A1KDM4EGLA | |
| SCHEMBL5846672 | 0.79 | TP53 (0.56) | AKR1C3AKR1C2TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8833711 | 0.78 | TP53 (0.55) | AKR1C3AKR1C2TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL5846278 | 0.77 | MAPT (0.52) | AKR1C3AKR1C2ALDH1A1MAPTKMT2A | |
| SCHEMBL8833701 | 0.75 | GAA (0.62) | AKR1C3AKR1C2ALDH1A1KDM4EGLA | |
| SCHEMBL11648417 | 0.74 | MAPT (0.42) | AKR1C3TAS1R3TAS1R1ALDH1A1GAA | |
| SCHEMBL8834506 | 0.73 | AKR1C3 (0.67) | AKR1C3AKR1C2ALDH1A1KDM4EGAA | |
| SCHEMBL10074768 | 0.73 | AKR1C3 (0.73) | AKR1C3AKR1C2ALDH1A1KDM4EMAPT | |
| SCHEMBL8834135 | 0.73 | AKR1C3 (0.55) | AKR1C3AKR1C2ALDH1A1KDM4EGAA | |
| SCHEMBL22720113 | 0.72 | MEN1 (0.72) | AKR1C3AKR1C2KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141312-B2 | Organic electroluminescent device based on 2,5-diaminoterephthalic acid derivatives | SENSIENT IMAGING TECHNOLOGIES GMBH (DE) | 2006-11-28 | — | — | US | disclosed |
| US-7112674-B2 | Organic electroluminescent device based on 2,5-diaminoterephthalic acid derivatives | SENSIENT IMAGING TECHNOLOGIES GMBH (DE) | 2006-09-26 | — | — | US | disclosed |
| US-20050025992-A1 | Organic electroluminescent device based on 2,5-diaminoterephthalic acid derivatives | RICHTER ANDREAS (DE) | 2005-02-03 | — | — | US | disclosed |
| US-20050003230-A1 | Organic electroluminescent device and based on 2,5-diaminoterephthalic acid derivatives | SENSIENT IMAGING TECHNOLOGIES GMBH (DE) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050003230-A1 | Organic electroluminescent device and based on 2,5-diaminoterephthalic acid derivatives | NPY4R, NPY5R, NPY1R | AKR1C3 784/4885AKR1C2 1448/4885TAS1R3 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.