Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846370 | 0.94 | PPARD (0.46) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5845152 | 0.85 | PPARD (0.45) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5846793 | 0.84 | PPARD (0.47) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL376890 | 0.82 | PPARG (0.49) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL7101627 | 0.79 | PPARG (0.51) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5845384 | 0.78 | PPARD (0.47) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5846365 | 0.78 | PPARD (0.46) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5845568 | 0.78 | PPARG (0.51) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5845540 | 0.77 | PPARD (0.45) | PPARGPPARDPPARASMN1; SMN2TP53 | |
| SCHEMBL5846647 | 0.76 | PPARD (0.52) | PPARGPPARDPPARASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078422-B2 | Activator for peroxisome proliferator-activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2006-07-18 | — | — | US | disclosed |
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| EP-1371650-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152744-A1 | Activator for peroxisome proliferator- activated receptor | PPARA, PPARG, PPARD | PPARG 2/4885PPARD 3/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.