SCHEMBL5848040

SCHEMBL5848040

O=C(O)C=Cc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1

nearest known ligand 0.87

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.87
LMNA P02545 2/20 0.87
AKR1C3 P42330 7/20 0.75
ALDH1A1 P00352 4/20 0.66
PKM P14618 1/20 0.66
APP P05067 3/20 0.65
THRB P10828 1/20 0.65
AKR1C4 P17516 1/20 0.64
AKR1C1 Q04828 1/20 0.64
PTGER4 P35408 1/20 0.63
PTGER3 P43115 1/20 0.63
PTGER2 P43116 1/20 0.63
HPGD P15428 2/20 0.61
HTT P42858 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27833553 1.00 KDM4E (0.87) KDM4ELMNAAKR1C3ALDH1A1PKM
SCHEMBL5848038 1.00 KDM4E (0.87) KDM4ELMNAAKR1C3ALDH1A1PKM
SCHEMBL1609268 0.92 KDM4E (0.79) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL1608802 0.92 KDM4E (0.79) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL1609269 0.92 KDM4E (0.79) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL1608804 0.92 KDM4E (0.79) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL11179981 0.91 KDM4E (0.74) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL6034563 0.91 KDM4E (0.78) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL6034559 0.91 KDM4E (0.78) KDM4ELMNAAKR1C3ALDH1A1APP
SCHEMBL20586637 0.90 KDM4E (0.72) KDM4ELMNAAKR1C3ALDH1A1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026518-B2 Resveratrol analogs LAILA IMPEX (IN) 2006-04-11 US disclosed
US-20040209951-A1 Novel resveratrol analogs LAILA IMPEX (IN) 2004-10-21 US disclosed
WO-2004000302-A1 NOVEL RESVERATROL ANALOGS GOKARAJU GANGA RAJU (IN) 2003-12-31 WO disclosed
WO-2003029183-A1 METHOD OF SYNTHESISING CHICORIC ACID UNIVERSITE DE BORDEAUX I (FR) 2003-04-10 WO disclosed
US-6048875-A CARDIOVASCULAR DISORDERS; REDUCING THROMBOSIS ADIR ET COMPAGNIE (FR) 2000-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209951-A1 Novel resveratrol analogs HRH1, CBR1, CBR3 KDM4E 1415/4885LMNA 4337/4885AKR1C3 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.