Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12251322 | 0.85 | MAPK1 (0.41) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL12251360 | 0.81 | AKR1C4 (0.39) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL12251273 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CASP1TP53TSHRSMN1; SMN2 | |
| SCHEMBL8152700 | 0.74 | AKR1C4 (0.68) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL29154613 | 0.74 | AKR1C2 (0.39) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL5671303 | 0.74 | AKR1C4 (0.61) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL25952739 | 0.73 | CYP3A4 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL10222516 | 0.73 | TSHR (0.57) | AKR1C2AKR1C1AKR1C3ALDH1A1TSHR | |
| SCHEMBL1614866 | 0.73 | AKR1C4 (0.65) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 | |
| SCHEMBL9246935 | 0.72 | AKR1C2 (0.58) | AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060210812-A1 | Insulating film and method of forming the same | JSR CORPORATION (JP) | 2006-09-21 | — | — | US | disclosed |