Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849924 | 0.90 | PRCP (0.50) | CHRNA7SMN1; SMN2ACACBHTTHDAC4 | |
| SCHEMBL30794389 | 0.90 | PRCP (0.50) | CHRNA7ACACBHTTHDAC4HDAC3 | |
| SCHEMBL5677149 | 0.90 | PRCP (0.50) | CHRNA7ACACBHTTHDAC4HDAC3 | |
| SCHEMBL30794373 | 0.89 | ACACB (0.45) | CHRNA7NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL5848047 | 0.89 | ACACB (0.45) | CHRNA7NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL30795640 | 0.86 | ACACB (0.45) | CHRNA7SMN1; SMN2ACACBHTTHDAC4 | |
| SCHEMBL5848291 | 0.86 | HTT (0.46) | CHRNA7ACACBHTTHDAC4HDAC3 | |
| SCHEMBL5679372 | 0.86 | ACACB (0.45) | CHRNA7SMN1; SMN2ACACBHTTHDAC4 | |
| SCHEMBL19146532 | 0.81 | ROCK2 (0.42) | CHRNA7ACACBHTTHDAC4HDAC3 | |
| SCHEMBL20559175 | 0.81 | ROCK2 (0.42) | CHRNA7ACACBHTTHDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144881-B2 | Arylcyclopropylcarboxylic amides as potassium channel openers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-12-05 | — | — | US | disclosed |