Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 9/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772958 | 1.00 | TSHR (0.33) | TSHRTHRBGGPS1SMPD1EPHX1 | |
| SCHEMBL16497335 | 0.94 | OPRM1 (0.30) | — | |
| SCHEMBL16496987 | 0.89 | — | — | |
| SCHEMBL16497514 | 0.85 | — | — | |
| SCHEMBL2122903 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2120583 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2120121 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL610797 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL2120675 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL959827 | 0.82 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6998040-B2 | Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography | UNIVERSITY OF SOUTH FLORIDA (US) | 2006-02-14 | — | — | US | disclosed |
| WO-2002059591-A9 | SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY | UNIV SOUTH FLORIDA (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20030075447-A1 | Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography | UNIVERSITY OF SOUTH FLORIDA | 2003-04-24 | — | — | US | disclosed |
| WO-2002059591-A1 | SOL-GEL OPEN TUBULAR ODS COLUMNS WITH CHARGED INNER SURFACE FOR CAPILLARY ELECTROCHROMATOGRAPHY | UNIVERSITY OF SOUTH FLORIDA (US) | 2002-08-01 | — | — | WO | disclosed |