Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 15/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552204 | 0.91 | TSHR (0.48) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL9845018 | 0.91 | TSHR (0.48) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL9516253 | 0.91 | TSHR (0.48) | TSHRKDM4EHTTTDP1KCNH2 | |
| Acetic Acid SCHEMBL30496778 | 0.88 | TSHR (0.46) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL17035690 | 0.88 | TSHR (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL17035688 | 0.88 | TSHR (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL4097947 | 0.84 | KCNH2 (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL3700192 | 0.81 | KCNH2 (0.60) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL31033436 | 0.81 | KCNH2 (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL3700194 | 0.81 | KCNH2 (0.60) | TSHRKDM4EHTTTDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878303-B1 | Compound for aromatherapy, aromatherapy medicine and aromatology | HEFTI DORIS (CH) | 2017-11-15 | — | — | EP | claimed |
| EP-2849718-B1 | MIXTURES HAVING IMPROVED COOLING EFFECT | SYMRISE AG (DE) | 2017-02-01 | — | — | EP | claimed |
| US-20150150922-A1 | COMPOSITION FOR USE IN AROMATHERAPY, AROMA MEDICINE AND AROMATOLOGY | HEFTI DORIS (CH) | 2015-06-04 | — | — | US | claimed |
| EP-2878303-A1 | Compound for aromatherapy, aromatherapy medicine and aromatology | Hefti, Doris (CH) | 2015-06-03 | — | — | EP | claimed |
| EP-2849718-A2 | MIXTURES HAVING IMPROVED COOLING EFFECT | Symrise AG (DE) | 2015-03-25 | — | — | EP | claimed |
| WO-2013171018-A2 | MIXTURES HAVING IMPROVED COOLING EFFECT | SYMRISE AG (DE) | 2013-11-21 | — | — | WO | claimed |
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |
| EP-1697386-B1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GEN ELECTRIC (US) | 2007-10-10 | — | — | EP | claimed |
| EP-0018679-B1 | SURFACTANT CAKE COMPOSITIONS CONTAINING SOLUBILITY REDUCING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1983-03-16 | — | — | EP | claimed |
| EP-3663366-B1 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2025-01-08 | — | — | EP | disclosed |
| EP-2145042-B2 | TEXTILE SCENTING | HENKEL AG & CO KGAA (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-2758041-B1 | LOW-MOLECULAR MODULATORS OF THE COLD-MENTHOL RECEPTOR TRPM8 AND USE OF SAME | BASF SE (DE) | 2021-01-13 | — | — | EP | disclosed |
| EP-2501761-B1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | SYMRISE AG (DE) | 2020-06-17 | — | — | EP | disclosed |
| EP-3663366-A2 | USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS | Symrise AG (DE) | 2020-06-10 | — | — | EP | disclosed |
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-1248532-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE | Symrise GmbH & Co. KG (DE) | 2002-10-16 | — | — | EP | disclosed |
| WO-2002051263-A1 | SELECTION METHOD FOR AROMATIC SUBSTANCES | HAARMANN & REIMER GMBH (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | disclosed |
| WO-2001043567-A1 | AROMAS AND AROMA COMPOSITIONS CONTAINING 4,8-DIMETHYL-3,7-NONADIEN-2-ONE, AND A METHOD FOR THE PRODUCTION THEREOF | HAARMANN & REIMER GMBH (DE) | 2001-06-21 | — | — | WO | disclosed |
| EP-1050574-A2 | Mint and/or fruit flavour compositions | HAARMANN & REIMER GMBH (DE) | 2000-11-08 | — | — | EP | disclosed |