Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 15/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552204 | 1.00 | TSHR (0.48) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL9845018 | 1.00 | TSHR (0.48) | TSHRKDM4EHTTTDP1KCNH2 | |
| Acetic Acid SCHEMBL30496778 | 0.97 | TSHR (0.46) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL584857 | 0.91 | TSHR (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL17035688 | 0.82 | TSHR (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL17035690 | 0.82 | TSHR (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL31033376 | 0.81 | TSHR (0.52) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL31033380 | 0.81 | TSHR (0.52) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL4097947 | 0.81 | KCNH2 (0.50) | TSHRKDM4EHTTTDP1KCNH2 | |
| SCHEMBL17106299 | 0.80 | TSHR (0.51) | TSHRKDM4EHTTTDP1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406742-B1 | PROCESS FOR THE PREPARATION OF CIS-DIHYDRONOPOL | Kali-Chemie Pharma GmbH (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0406742-A1 | Process for the preparation of cis-dihydronopol | Kali-Chemie Pharma GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |