⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2679704 | 0.97 | KDM4E (0.34) | — | |
| SCHEMBL29505972 | 0.89 | — | — | |
| SCHEMBL22402225 | 0.89 | — | — | |
| Piperazine SCHEMBL9824675 | 0.83 | HIF1A (0.32) | — | |
| SCHEMBL14222410 | 0.81 | — | — | |
| SCHEMBL4515477 | 0.81 | — | — | |
| SCHEMBL14222411 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL25189965 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7011180 | 0.79 | — | — | |
| SCHEMBL71836 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974865-B | Preparation and application of 1,3, 4-thiadiazole compounds | 潍坊医学院附属医院 | 2025-03-07 | — | — | CN | claimed |
| CN-114341124-B | Protein tyrosine phosphatase inhibitors | ARRAY生物制药公司 | 2024-09-20 | — | — | CN | claimed |
| CN-114957162-B | Preparation and application of thiadiazole parent nucleus compound | 潍坊医学院附属医院 | 2024-03-12 | — | — | CN | claimed |
| CN-115974865-A | Preparation and application of 1,3,4-thiadiazole compounds | 潍坊医学院附属医院 | 2023-04-18 | — | — | CN | claimed |
| CN-114957162-A | Preparation and application of thiadiazole parent nucleus compound | 潍坊医学院附属医院 | 2022-08-30 | — | — | CN | claimed |
| CN-112080259-B | Shale intercalation inhibitor prepared from environment-friendly hyperbranched polyquaternary ammonium salt amino acid | 西南石油大学 | 2022-04-01 | — | — | CN | claimed |
| CN-112441970-A | 2, 5-disubstituted-3-aminopyridine compound and preparation method and application thereof | 天津医科大学 | 2021-03-05 | — | — | CN | claimed |
| CN-112080259-A | Shale intercalation inhibitor prepared from environment-friendly hyperbranched polyquaternary ammonium salt amino acid | 西南石油大学 | 2020-12-15 | — | — | CN | claimed |
| EP-3191478-A1 | COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS | Novartis AG (CH) | 2017-07-19 | — | — | EP | claimed |
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | claimed |
| EP-2676666-A1 | Compounds for use in diagnosis or therapy of vulnerable atherosclerotic plaques | Eidgenössische Technische Hochschule Zürich (ETH) (CH) | 2013-12-25 | — | — | EP | claimed |
| US-20130085128-A1 | 6-(4-Hydroxy-phenyl)-3-alkyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-04-04 | — | — | US | claimed |
| WO-2013045413-A1 | 6-(4-HYDROXY-PHENYL)-3-ALKYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI (FR) | 2013-04-04 | — | — | WO | claimed |
| WO-2013037390-A1 | 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI (FR) | 2013-03-21 | — | — | WO | claimed |
| US-20130065894-A1 | 6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS | SANOFI (FR) | 2013-03-14 | — | — | US | claimed |
| EP-2567959-A1 | 6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-03-13 | — | — | EP | claimed |
| US-8354444-B2 | Substituted pyrrolidine-2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 2013-01-15 | — | — | US | claimed |
| EP-2534132-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-12-19 | — | — | EP | claimed |
| EP-2535338-A1 | Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile | Abbott Laboratories (US) | 2012-12-19 | — | — | EP | claimed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | claimed |