⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL457944 | 0.95 | — | — | |
| SCHEMBL3106063 | 0.95 | ALDH1A1 (0.43) | — | |
| Bromide SCHEMBL6622782 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL8308716 | 0.95 | — | — | |
| SCHEMBL986591 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL17981698 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL30536202 | 0.91 | ALDH1A1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL29482099 | 0.91 | ALDH1A1 (0.41) | — | |
| SCHEMBL23888860 | 0.87 | ALDH1A1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL5914602 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124474-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2024-04-18 | — | — | US | claimed |
| CN-117886737-A | Spiroteine framework compound and preparation method and application thereof | 安徽农业大学 | 2024-04-16 | — | — | CN | claimed |
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | claimed |
| US-20230023851-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2023-01-26 | — | — | US | claimed |
| US-10155770-B2 | Substituted pyrazolopyrimidines and method of use | ABBVIE INC. (US) | 2018-12-18 | — | — | US | claimed |
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | claimed |
| EP-3286192-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND METHOD OF USE | AbbVie Deutschland GmbH & Co KG (DE) | 2018-02-28 | — | — | EP | claimed |
| US-9828381-B2 | Substituted pyrazolopyrimidines and method of use | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-11-28 | — | — | US | claimed |
| US-9718785-B2 | 1,3-Disubstituted cyclopentane derivatives | MERCK PATENT GMBH (DE) | 2017-08-01 | — | — | US | claimed |
| US-9693997-B2 | Antiviral compounds | HOFFMANN-LA ROCHE INC. (US) | 2017-07-04 | — | — | US | claimed |
| WO-2002010116-A2 | PROCESS FOR THE PREPARATION OF ALKYL 1-METHYLCYCLOPROPANECARBOXYLATE | EASTMAN CHEMICAL COMPANY (US) | 2002-02-07 | — | — | WO | claimed |
| EP-0870756-B1 | Process for the preparation of 3,4-disubstituted dinitroanilines | CFPI NUFARM (FR) | 2001-11-07 | — | — | EP | claimed |
| EP-0677514-B1 | CYCLOPROPYL DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATIONS | INST INVESTIGACION DESARROLLO (ES) | 1999-12-29 | — | — | EP | claimed |
| US-5834490-A | Cyclopropyl derivatives, preparation method there-of and applications | INSTITUTO DE INVESTIGACION Y DESARROLO QUIMICO BIOLOGICO, S.A. (ES) | 1998-11-10 | — | — | US | claimed |
| US-5602244-A | DINUCLEOSIDE PRECURSORS IN OLIGONUCLEOTIDE SYNTHESIS; USEFUL AS ANTISENSE INHIBITORS OF TRANSLATION | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-02-11 | — | — | US | claimed |
| EP-0677514-A1 | NEW CYCLOPROPYL DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATIONS | INSTITUTO DE INVESTIGACION Y DESARROLLO QUIMICO-BIOLOGICO S.A. (ES) | 1995-10-18 | — | — | EP | claimed |
| EP-0144386-B1 | NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES | BECKMAN INSTRUMENTS, INC. (US) | 1989-09-06 | — | — | EP | claimed |
| EP-0144386-A1 | NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES. | BECKMAN INSTRUMENTS INC (US) | 1985-06-19 | — | — | EP | claimed |
| WO-1984004749-A1 | NOVEL PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITE INTERMEDIATES | BECKMAN INSTRUMENTS INC (US) | 1984-12-06 | — | — | WO | claimed |
| US-4054739-A | Process for the substitution of chlorine atoms of cyanuric chloride | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-10-18 | — | — | US | claimed |