SCHEMBL584864

SCHEMBL584864

O=S(=O)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.56
CA1 P00915 13/20 0.52
MMP1 P03956 4/20 0.52
MMP2 P08253 4/20 0.52
MMP9 P14780 4/20 0.52
MMP8 P22894 4/20 0.52
MMP13 P45452 4/20 0.52
F2 P00734 4/20 0.46
PRSS1 P07477 4/20 0.46
PRSS2 P07478 4/20 0.46
PRSS3 P35030 4/20 0.46
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585308 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL302264 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL584177 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL585171 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL3838335 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL7660482 1.00 CA2 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL73684 0.97 CA2 (0.52) CA2CA1MMP1MMP2MMP9
SCHEMBL6898759 0.94 CA2 (0.50) CA2CA1MMP1MMP2MMP9
SCHEMBL13684270 0.91 CA2 (0.43) CA2CA1MMP1MMP2MMP9
SCHEMBL11788241 0.91 CA2 (0.43) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104119238-B A kind of preparation method of 4-(a chlorine difluoro-methoxy) aniline 金凯(辽宁)化工有限公司 2016-09-21 CN claimed
CN-103553884-B Method for preparing trifluoromethoxybenzene KINGCHEM LIAONING CHEMICAL CO LTD 2015-03-25 CN claimed
CN-103274929-B Preparation method of 2-trifluoromethyl benzoic acid KINGCHEM LIAONING CHEMICAL CO LTD 2014-12-17 CN claimed
US-8906454-B2 Methods for depositing metal-polymer composite materials atop a substrate APPLIED MATERIALS, INC. (US) 2014-12-09 US claimed
WO-2013039862-A2 METHODS FOR DEPOSITING METAL-POLYMER COMPOSITE MATERIALS ATOP A SUBSTRATE APPLIED MATERIALS, INC. (US) 2013-03-21 WO claimed
US-20130065401-A1 METHODS FOR DEPOSITING METAL-POLYMER COMPOSITE MATERIALS ATOP A SUBSTRATE APPLIED MATERIALS, INC. (US) 2013-03-14 US claimed
US-10876034-B1 Modified silicon dioxide material of fluorocarbon active agent type super-amphiphobic cutting-carrying agent suitable for water-based drilling fluid and preparation method thereof CHINA UNIVERSITY OF PETROLEUM (BEIJING) (CN) 2020-12-29 US disclosed
CN-109337657-B Modified silicon dioxide material suitable for fluorocarbon active agent type super-amphiphobic chip carrying agent for water-based drilling fluid and preparation method and application thereof 中国石油大学(北京) 2020-04-24 CN disclosed
CN-109337657-A The improved silica material and its preparation method and application of bits agent is taken with fluorine carbon activity agent class super-amphiphobic suitable for water-base drilling fluid 中国石油大学(北京) 2019-02-15 CN disclosed
US-20170283960-A1 METHOD OF DISCOVERING FLUORO-CONTAINING COMPOUNDS SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) 2017-10-05 US disclosed
CN-104119238-B A kind of preparation method of 4-(a chlorine difluoro-methoxy) aniline 金凯(辽宁)化工有限公司 2016-09-21 CN disclosed
WO-2016106161-A1 METHOD OF DISCOVERING FLUORO-CONTAINING COMPOUNDS SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD. (CN) 2016-06-30 WO disclosed
CN-103553884-B Method for preparing trifluoromethoxybenzene KINGCHEM LIAONING CHEMICAL CO LTD 2015-03-25 CN disclosed
US-20010017268-A1 Electrochemical fluorination using interrupted current 3M INNOVATIVE PROPERTIES COMPANY 2001-08-30 US disclosed
US-6267865-B1 USING ELECTROLYTIC CELL 3M INNOVATIVE PROPERTIES COMPANY 2001-07-31 US disclosed
EP-1080251-A1 ELECTROCHEMICAL FLUORINATION OF ALKANE SUBSTRATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2001-03-07 EP disclosed
WO-1999058745-A1 ELECTROCHEMICAL FLUORINATION OF ALKANE SUBSTRATE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-11-18 WO disclosed
EP-0643155-B1 Process for preparing fluorochemicals MINNESOTA MINING & MFG (US) 1998-10-28 EP disclosed
EP-0643155-A2 Process for preparing fluorochemicals MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-15 EP disclosed
US-5387323-A Process for preparing fluorochemicals MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-07 US disclosed