Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 5/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.37 |
| ▸ | TFPI | P10646 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849482 | 1.00 | OPRL1 (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL13496859 | 0.93 | NPY4R (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL7394659 | 0.93 | NPY4R (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL31410639 | 0.92 | NPY4R (0.47) | CXCR4NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29489381 | 0.92 | OPRL1 (0.44) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL30753507 | 0.91 | PTGS1 (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL25639021 | 0.91 | PTGS1 (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL29647783 | 0.91 | PTGS1 (0.40) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL17440322 | 0.91 | QRFPR (0.42) | OPRL1CXCR4NPY4RNPY1RNPY2R | |
| SCHEMBL13319653 | 0.91 | QRFPR (0.42) | OPRL1CXCR4NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087722-B1 | Fibrin binding domain polypeptides and uses and methods of producing same | SAVIENT PHARMACEUTICALS, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-6121426-A | IMAGING POLYPEPTIDE LABELED WITH A MARKER; FOR THE PREVENTION OF INFECTION AND SEPSIS IN WOUNDS; FOR THE DETECTION OF ATHEROSCLEROTIC PLAQUES OR THROMBUS | BIO-TECHNOLOGY GENERAL CORP. (US) | 2000-09-19 | — | — | US | disclosed |
| US-5965383-A | IMAGING AGENT OF A LABELED POLYPEPTIDE WHICH IS A FIBRIN BINDING DOMAIN FROM FIBRONECTIN; FOR DIAGNOSIS OF ATHLEROSCLEROTIC PLAQUE AND THROMBI | BIO-TECHNOLOGY GENERAL CORP. (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0651799-B1 | FIBRIN BINDING DOMAIN POLYPEPTIDES AND USES AND METHODS OF PRODUCING SAME | BIO TECHNOLOGY GENERAL CORP (US) | 1999-08-18 | — | — | EP | disclosed |
| US-5869616-A | IMAGING AGENT COMPOSED OF N-TERMINAL AMINO ACID SEQUENCE OF FIBRONECTIN AND LABEL; FOR NONINVASIVE, ACCURATE DIAGNOSIS OF A THROMBUS OR ATHEROSCLEROTIC PLAQUE | BIO-TECHNOLOGY GENERAL CORP. (US) | 1999-02-09 | — | — | US | disclosed |
| US-5679320-A | IMAGING FIBRIN CONTAINING SUBSTANCE BY CONTACTING WITH POLYPEPTIDE HAVING AMINO ACID SEQUENCE IDENTICAL TO FIBRIN BINDING DOMAIN OF HUMAN FIBRONECTIN LABELED WITH IMAGEABLE MARKER | BIO-TECHNOLOGY GENERAL CORP. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5455158-A | Imaging fibrin-containing substance using labeled polypeptide imaging agent which binds to fibrin | BIO-TECHNOLOGY GENERAL CORP. (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0651799-A1 | FIBRIN BINDING DOMAIN POLYPEPTIDES AND USES AND METHODS OF PRODUCING SAME | BIO-TECHNOLOGY GENERAL CORPORATION (US) | 1995-05-10 | — | — | EP | disclosed |
| US-5270030-A | Fibrin binding domain polypeptide and method of producing | BIO-TECHNOLOGY GENERAL CORP. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0651799-A4 | FIBRIN BINDING DOMAIN POLYPEPTIDES AND USES AND METHODS OF PRODUCING SAME. | BIO TECHNOLOGY GENERAL CORP (US) | 1993-10-05 | — | — | EP | disclosed |
| WO-1991017765-A1 | FIBRIN BINDING DOMAIN POLYPEPTIDES AND USES AND METHODS OF PRODUCING SAME | BIO-TECHNOLOGY GENERAL CORP. (US) | 1991-11-28 | — | — | WO | disclosed |