SCHEMBL29489381

SCHEMBL29489381

N=C(N)NCCC[C@H](NC(=O)CNC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 3/20 0.44
NMT2 O60551 2/20 0.43
NMT1 P30419 2/20 0.43
CXCR4 P61073 2/20 0.42
NPY4R P50391 3/20 0.41
NPY1R P25929 2/20 0.41
NPY2R P49146 2/20 0.41
NPY5R Q15761 2/20 0.41
TFPI P10646 1/20 0.41
TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31410685 0.98 NPY4R (0.43) OPRL1NMT2NMT1CXCR4NPY4R
SCHEMBL29642947 0.96 TFPI (0.44) OPRL1NMT2NMT1CXCR4NPY4R
SCHEMBL30521941 0.95 OPRL1 (0.43) OPRL1NMT2NMT1CXCR4NPY4R
SCHEMBL31343536 0.94 NPY4R (0.45) OPRL1NMT2NMT1CXCR4NPY4R
SCHEMBL31343396 0.94 NPY4R (0.45) OPRL1NMT2NMT1CXCR4NPY4R
SCHEMBL30063019 0.93 NPY4R (0.42) OPRL1CXCR4NPY4RNPY1RNPY2R
SCHEMBL7394659 0.92 NPY4R (0.40) OPRL1CXCR4NPY4RNPY1RNPY2R
SCHEMBL13496859 0.92 NPY4R (0.40) OPRL1CXCR4NPY4RNPY1RNPY2R
SCHEMBL13655538 0.92 NMT1 (0.45) OPRL1NMT2NMT1NPY4RNPY1R
SCHEMBL5849470 0.92 OPRL1 (0.40) OPRL1CXCR4NPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207308-A1 METHOD FOR CULTURING DENDRITIC CELLS NANOFAENTECH CO., Ltd. (KR) 2024-06-27 US disclosed
EP-4335919-A1 METHOD FOR CULTURING DENDRITIC CELLS Nanofaentech Co., Ltd. (KR) 2024-03-13 EP disclosed
WO-2022235072-A1 METHOD FOR CULTURING DENDRITIC CELLS 아주대학교산학협력단 2022-11-10 WO disclosed
US-11291407-B2 Detection of high risk drusen APELLIS PHARMACEUTICALS, INC. (US) 2022-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291407-B2 Detection of high risk drusen EXOSC4, EXOSC5, EXOSC10 OPRL1 2074/4885NMT2 3661/4885NMT1 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.