Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 1.00 |
| ▸ | ITGAV | P06756 | 20/20 | 1.00 |
| ▸ | ITGB6 | P18564 | 13/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847444 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL5847853 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGA2B | |
| Hydrochloric Acid SCHEMBL5849637 | 0.99 | ITGB3 (0.98) | ITGB3ITGAVITGB6ITGA2B | |
| Hydrochloric Acid SCHEMBL5847852 | 0.99 | ITGB3 (0.98) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL5847771 | 0.92 | ITGB3 (0.85) | ITGB3ITGAVITGB6ITGA2B | |
| Hydrochloric Acid SCHEMBL5848066 | 0.91 | ITGB3 (0.84) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL5847713 | 0.89 | ITGAV (0.81) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL8309180 | 0.89 | ITGAV (0.81) | ITGB3ITGAVITGB6ITGA2B | |
| Hydrochloric Acid SCHEMBL5847935 | 0.89 | ITGAV (0.80) | ITGB3ITGAVITGB6ITGA2B | |
| SCHEMBL5849800 | 0.87 | ITGB3 (1.00) | ITGB3ITGAVITGB6ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115596-B2 | Thiazole compounds as integrin receptor antagonists derivatives | PHARMACIA CORPORATION (US) | 2006-10-03 | — | — | US | claimed |
| EP-1572690-A1 | THIAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | Pharmacia Corporation (US) | 2005-09-14 | — | — | EP | claimed |
| US-20050004189-A1 | Thiazole compounds as integrin receptor antagonists derivatives | PHARMACIA CORPORATION | 2005-01-06 | — | — | US | claimed |
| WO-2004058760-A1 | THIAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | claimed |
| WO-2004058760-A1 | THIAZOLE COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES | PHARMACIA CORPORATION (US) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004189-A1 | Thiazole compounds as integrin receptor antagonists derivatives | ITGA5, ITGB5, ITGAL | ITGB3 4/4885ITGAV 5/4885ITGB6 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.