SCHEMBL5849644

SCHEMBL5849644

CCCCCCCCCCCCCCCCCCC(C(=O)OCC)C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ZDHHC7 Q9NXF8 1/20 0.50
L3MBTL1 Q9Y468 4/20 0.48
MAPT P10636 3/20 0.48
GPR84 Q9NQS5 5/20 0.47
FFAR1 O14842 1/20 0.47
MAPK1 P28482 2/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
LCK P06239 1/20 0.45
PPARD Q03181 1/20 0.45
ZDHHC20 Q5W0Z9 1/20 0.45
ZDHHC2 Q9UIJ5 1/20 0.45
CPB2 Q96IY4 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7508355 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL7775862 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL5860379 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL10017368 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL2948251 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL4416096 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL6828633 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL9116048 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL182928 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1
SCHEMBL1433359 1.00 TDP1 (0.50) TDP1MEN1KMT2AZDHHC7L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10647738-B2 Xylene-based amphiphilic compound and use thereof INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2020-05-12 US disclosed
US-20180273570-A1 NOVEL XYLENE-BASED AMPHIPHILIC COMPOUND AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2018-09-27 US disclosed
WO-2017039107-A1 NEW XYLENE-BASED AMPHIPATHIC COMPOUND AND USE THEREOF 한양대학교 에리카산학협력단 2017-03-09 WO disclosed
CN-105287363-A Micromolecular organic gel for orthotopic injection and preparation method and application thereof GANNAN NORMAL UNIVERSITY 2016-02-03 CN disclosed
US-7078159-B2 Method for the preparation of a printing plate EASTMAN KODAK COMPANY (US) 2006-07-18 US disclosed
EP-1386729-A1 Method for the preparation of a printing plate EASTMAN KODAK COMPANY (US) 2004-02-04 EP disclosed
US-20040018447-A1 Method for the preparation of a printing plate EASTMAN KODAK COMPANY 2004-01-29 US disclosed
EP-0121088-B1 NEW O-ACYL-ALKANEDIOL-PHOSPHOLIPIDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM A. Nattermann & Cie. GmbH (DE) 1986-10-01 EP disclosed
US-4610979-A O-acyl-alkanediol-phospholipids and processes for the treatment of asthma A. NATTERMANN & CIE GMBH (DE) 1986-09-09 US disclosed
EP-0121088-A1 New o-acyl-alkanediol-phospholipids, processes for their preparation and pharmaceutical preparations containing them A. Nattermann & Cie. GmbH (DE) 1984-10-10 EP disclosed
EP-0112344-A1 AMPHIPATHIC COMPOUNDS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-07-04 EP disclosed
WO-1983004412-A1 AMPHIPATHIC COMPOUNDS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180273570-A1 NOVEL XYLENE-BASED AMPHIPHILIC COMPOUND AND USE THEREOF PEX14, SLC47A2, PXMP4 TDP1 3894/4885MEN1 3834/4885KMT2A 3018/4885
US-10647738-B2 Xylene-based amphiphilic compound and use thereof PEX14, PXMP4, SLC47A2 TDP1 3714/4885MEN1 3487/4885KMT2A 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.