Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.67 |
| ▸ | PDE4A | P27815 | 18/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414604 | 0.91 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7414607 | 0.91 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7786887 | 0.91 | PDE4B (0.54) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL14074068 | 0.90 | PDE4B (0.68) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL1030816 | 0.86 | PDE4B (0.64) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL6816588 | 0.86 | PDE4B (0.78) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7793438 | 0.86 | PDE4A (0.76) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7793227 | 0.86 | PDE4A (0.76) | PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL7530836 | 0.86 | PDE4A (0.76) | PDE4BPDE4DPDE4APDE4C | |
| Hydrochloric Acid SCHEMBL1032550 | 0.85 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101866-B2 | 6,9-Difluoro-17 alpha -((2-furanylcarbonyl)oxy)-11 beta -hydroxy-16 alpha -methyl-3-oxo-androsta-1,4-diene-17 beta -carbothioic acid S-fluoromethyl ester; antiinflammatory agents for the treatment of allergic conditions | GLAXO GROUP LIMITED (GB) | 2006-09-05 | — | — | US | claimed |