Acetic Acid

Acetic Acid

SCHEMBL585034

C=COC(=O)C1CC1.CC(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.36
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9421500 0.91 KMT2A (0.36) KMT2ATHRATHRBLMNAALDH1A1
SCHEMBL5528 0.91
SCHEMBL295509 0.91 KMT2A (0.41) KMT2ATHRATHRB
Methacrylic Acid SCHEMBL1248311 0.90 KMT2A (0.33) KMT2ATHRATHRBLMNATSHR
SCHEMBL994923 0.89 KMT2A (0.35) KMT2ATHRATHRBALDH1A1TSHR
Formaldehyde SCHEMBL9633220 0.89 KMT2A (0.40) KMT2ATHRATHRB
Hydrochloric Acid SCHEMBL10608471 0.89
Charcoal, Activated SCHEMBL8216968 0.89
Water SCHEMBL9815377 0.89
SCHEMBL16176164 0.87 PLG (0.39) KMT2ALMNATSHRELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408296-A1 Comfortable ostomy pouch W.R. Grace & Co.-Conn. (US) 1991-01-16 EP claimed
US-4983171-A Comfortable ostomy pouch W. R. GRACE & CO.-CONN. (US) 1991-01-08 US claimed
CN-211065245-U Cushioning sole and cushioning shoe with same 福建省晋江泉发骑士鞋业有限公司 2020-07-24 CN disclosed
CN-102803937-B copper bromide humidity indicating card 多种吸附技术公司 2016-06-29 CN disclosed
CN-102803937-A Copper bromide humidity indicating card MULTISORB TECH INC 2012-11-28 CN disclosed
EP-2417439-A2 COPPER BROMIDE HUMIDITY INDICATING CARD Multisorb Technologies, Inc. (US) 2012-02-15 EP disclosed
WO-2010117865-A2 COPPER BROMIDE HUMIDITY INDICATING CARD MULTISORB TECHNOLOGIES, INC. (US) 2010-10-14 WO disclosed
US-20100252779-A1 COPPER BROMIDE HUMIDITY INDICATING CARD MULTISORB TECHNOLOGIES, INC. (US) 2010-10-07 US disclosed
US-6238732-B1 PRESSURE SENSITIVE ADHESIVE H. B. FULLER LICENSING & FINANCING INC. 2001-05-29 US disclosed
US-6120899-A THERMOPLASTIC COMPOSITION COATED WITH A CONTINUOUS NONTACKY COATING SURROUNDING THE THERMOPLASTIC; FREE-FLOWING, BLOCKING RESISTANCE DURING STORAGE H. B. FULLER LICENSING & FINANCING INC. (US) 2000-09-19 US disclosed
EP-1023361-A1 HOT MELT ADHESIVE PELLET COMPRISING CONTINUOUS COATING OF PELLETIZING AID H.B. Fuller Licensing & Financing, Inc. (US) 2000-08-02 EP disclosed
WO-1999018147-A1 HOT MELT ADHESIVE PELLET COMPRISING CONTINUOUS COATING OF PELLETIZING AID H.B. FULLER LICENSING & FINANCING, INC. (US) 1999-04-15 WO disclosed
WO-1999018148-A1 COMPOSITION OF POWDER-COATED TACKY MATERIAL AND METHOD OF MAKING SAME H.B. FULLER LICENSING & FINANCING, INC. (US) 1999-04-15 WO disclosed
US-4983171-A Comfortable ostomy pouch W. R. GRACE & CO.-CONN. (US) 1991-01-08 US disclosed
US-4467916-A POLYMERIC FILM WRAPPING PPG INDUSTRIES, INC. (US) 1984-08-28 US disclosed