SCHEMBL994923

SCHEMBL994923

C=COC(=O)C1CC1.C=COC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9421500 0.89 KMT2A (0.36) KMT2ATHRATHRBHSD17B10TDP1
Acetic Acid SCHEMBL585034 0.89 KMT2A (0.36) KMT2ATHRATHRBALDH1A1TSHR
SCHEMBL295509 0.89 KMT2A (0.41) KMT2ATHRATHRBTDP1
SCHEMBL5528 0.89
Hydrochloric Acid SCHEMBL10608471 0.87
Water SCHEMBL9815377 0.87
Charcoal, Activated SCHEMBL8216968 0.87
Formaldehyde SCHEMBL9633220 0.87 KMT2A (0.40) KMT2ATHRATHRBTDP1
SCHEMBL3170410 0.85 KMT2A (0.39) KMT2ATHRATHRBTDP1
Methacrylic Acid SCHEMBL1248311 0.84 KMT2A (0.33) KMT2ATHRATHRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107097502-A Stick pack easily tears composite membrane and its manufacture method 浙江金石包装有限公司 2017-08-29 CN claimed
CN-106413695-B Rivastigmine transdermal compositions and methods of use thereof 帝国制药美国公司 2019-12-10 CN disclosed
CN-107768449-B Solar cell module LG电子株式会社 2019-11-05 CN disclosed
US-10357463-B2 Rivastigmine transdermal compositions and methods of using the same TEIKOKU PHARMA USA, INC. (US) 2019-07-23 US disclosed
CN-108641621-A A kind of metal surface pre-coating film and preparation method thereof 重庆新康意安得达尔新材料有限公司 2018-10-12 CN disclosed
US-20180193285-A1 Rivastigmine Transdermal Compositions and Methods of Using the Same TEIKOKU PHARMA USA, INC. 2018-07-12 US disclosed
CN-108047826-A A kind of organosilicon polymer complex emulsions and preparation method thereof 南通福伦利新材料有限公司 2018-05-18 CN disclosed
US-9949935-B2 Rivastigmine transdermal compositions and methods of using the same TEIKOKU PHARMA USA, INC. (US) 2018-04-24 US disclosed
CN-107768449-A Solar module LG电子株式会社 2018-03-06 CN disclosed
CN-105226120-B solar cell module LG电子株式会社 2017-12-01 CN disclosed
WO-2011003107-A2 A SEALABLE MATERIAL AND METHOD OF FORMING A DIELECTRIC WELD SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2011-01-06 WO disclosed
US-20110003104-A1 SEALABLE MATERIAL AND METHOD OF FORMING A DIELECTRIC WELD SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2011-01-06 US disclosed
EP-0938600-B1 Dental floss PERI DENT LTD (GB) 2006-12-06 EP disclosed
US-6303063-B1 Process of making a yarn PERI-DENT LIMITED (GB) 2001-10-16 US disclosed
EP-0938600-A1 PLASTICS MATERIALS YARN Peri-Dent Limited (GB) 1999-09-01 EP disclosed
WO-1998050607-A1 PLASTICS MATERIALS YARN PERI-DENT LIMITED (GB) 1998-11-12 WO disclosed
EP-0408296-A1 Comfortable ostomy pouch W.R. Grace & Co.-Conn. (US) 1991-01-16 EP disclosed
US-4915963-A MULTILAYER FILM USING ETHYLENE VINYL ACETATE AS INNER LAYER; SEALING, STUFFING VISKASE CORPORATION (US) 1990-04-10 US disclosed
US-4784863-A BARRIER LAYER AS CORE, ADHESION TO MEAT VISKASE CORPORATION (US) 1988-11-15 US disclosed
US-4749084-A Tamper-indicating package with randomly disposed filaments MINNESOTA MINING AND MANUFACTURING CO. (US) 1988-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10357463-B2 Rivastigmine transdermal compositions and methods of using the same ACHE, CHRNE, CHRNA7 KMT2A 722/4885THRA 1823/4885THRB 2610/4885
US-20180193285-A1 Rivastigmine Transdermal Compositions and Methods of Using the Same ACHE, CHRNE, CHRNA7 KMT2A 722/4885THRA 1823/4885THRB 2610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.