SCHEMBL5850501

SCHEMBL5850501

CCCC(Br)COP(=O)(OCl)OCC(Br)CCC

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
FDPS P14324 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5850497 0.80 CYP3A4 (0.37) CYP3A4L3MBTL1FDPS
SCHEMBL11378363 0.78 ALDH1A1 (0.33) CYP3A4L3MBTL1
SCHEMBL27264510 0.74 CYP3A4 (0.79) CYP3A4L3MBTL1FDPSTSHR
SCHEMBL5704246 0.73 CYP3A4 (0.56) CYP3A4L3MBTL1FDPS
SCHEMBL3685381 0.73 CYP3A4 (0.41) CYP3A4L3MBTL1TSHR
SCHEMBL6866308 0.70 CYP3A4 (0.33) CYP3A4L3MBTL1TSHR
SCHEMBL11587442 0.69 CYP3A4 (0.47) CYP3A4L3MBTL1FDPS
Acetic Acid SCHEMBL27476406 0.68 CYP3A4 (0.68) CYP3A4L3MBTL1TSHR
SCHEMBL5851904 0.68
SCHEMBL177847 0.68 CYP3A4 (0.50) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed